DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2577 and Csnk1a1

DIOPT Version :9

Sequence 1:	NP_572794.1	Gene:	CG2577 / 32188	FlyBaseID:	FBgn0030384	Length:	344	Species:	Drosophila melanogaster
Sequence 2:	XP_038952461.1	Gene:	Csnk1a1 / 113927	RGDID:	71098	Length:	374	Species:	Rattus norvegicus

Alignment Length:	358	Identity:	193/358 - (53%)
Similarity:	246/358 - (68%)	Gaps:	36/358 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GNYKVVRKIGCGSFGDIYLGIYIHSGERVAIKVESSKVRHPQLNYERRIYRALRPAHGLPRIRYF 79
            |.||:|||||.||||||||.|.|.:||.||:|:||.|.|||||.||.::|:.|:...|:|.||::
  Rat    15 GKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHIRWY 79

  Fly    80 HKEEHYQAMVMDLLGPSLERLFQFCERAFTIKTVLLLAEQMLRRVEYVHNRGFLHRDIKPDNFLM 144
            .:|:.|..:||||||||||.||.||.|.||:||||:||:||:.|:||||.:.|:|||||||||||
  Rat    80 GQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLM 144

  Fly   145 GLG------------------TMS----------KQVYLIDFGLSKKYLDITTGVHIPYREERSL 181
            |:|                  |:|          .|::||||||:|||.|..|..||||||:::|
  Rat   145 GIGRHCNKCLESPVGKRKRSMTVSPSQDPSFSGLNQLFLIDFGLAKKYRDNRTRQHIPYREDKNL 209

  Fly   182 TGTARYASIGAHAGVESARRDDMVAVGYVLMYFNRGSLPWQDLKASTKQQKYERIHEKKISVSIE 246
            |||||||||.||.|:|.:|||||.::|||||||||.|||||.|||:||:||||:|.|||:|..:|
  Rat   210 TGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVE 274

  Fly   247 VLCEGFPCEFTMYLNYCRGMGFYDKPNYDFICRMFRMLRNGLNLRPGLIYDWDMLMMK-FHNTQK 310
            |||:|||.||.||||||||:.|.:.|:|.::.::||:|...||.:....:||.||..| ......
  Rat   275 VLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAAS 339

  Fly   311 NPGIGMRVFPPKQKEDD----GISGEPIIKDEK 339
            :.|.|.:...|..|:.|    .:.|   |||||
  Rat   340 SSGQGQQAQTPTGKQTDKTKSNMKG---IKDEK 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2577	NP_572794.1	STKc_CK1	16..281	CDD:270918	171/292 (59%)
CG2577	NP_572794.1	SPS1	16..>242	CDD:223589	150/253 (59%)
Csnk1a1	XP_038952461.1	STKc_CK1_alpha	16..309	CDD:271030	171/292 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353377
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.960