DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ten-a and TNN

DIOPT Version :9

Sequence 1:NP_001162732.2 Gene:Ten-a / 32183 FlyBaseID:FBgn0267001 Length:3387 Species:Drosophila melanogaster
Sequence 2:XP_016857537.1 Gene:TNN / 63923 HGNCID:22942 Length:1317 Species:Homo sapiens


Alignment Length:192 Identity:69/192 - (35%)
Similarity:85/192 - (44%) Gaps:34/192 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   914 ELVAHSVSLLA--EEAEGVSTTCPNDCSGRGSCYLGKCDCIDGYQGV-DCSKSVCPVLCSAHGHY 975
            ||......|||  ::.|.........||.:..|           ||| |.|:.     ||.||.:
Human   118 ELAGSVQDLLARVKKLEEEMVEMKEQCSAQRCC-----------QGVTDLSRH-----CSGHGTF 166

  Fly   976 GGGV--CHCEEGWKGAECDIPVGECEVPN-CSSHGRCIEGECHCERGWKGPYCDQHDCLDPLCSG 1037
            ....  ||||||.:|..|:    ....|. ||.||||::|.|.|...:.|..|....|.:. |||
Human   167 SLETCSCHCEEGREGPACE----RLACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPEN-CSG 226

  Fly  1038 HGTCVAGQCYCKAGWQGEDCGTIDQQVYQCLPGCSEHGTYDLETGQCVCERHWTGPDCSQAV 1099
            ||.||.|.|.|...:..|||..     .:|...||.||..|  ||:|.||..:||.||:|.|
Human   227 HGECVRGVCQCHEDFMSEDCSE-----KRCPGDCSGHGFCD--TGECYCEEGFTGLDCAQVV 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ten-aNP_001162732.2 EGF_2 934..960 CDD:285248 6/26 (23%)
Keratin_B2 998..1162 CDD:279797 43/103 (42%)
EGF_2 <1003..1025 CDD:285248 10/21 (48%)
EGF_2 1032..1057 CDD:285248 11/24 (46%)
EGF_2 <1071..1095 CDD:285248 12/23 (52%)
EGF_2 1101..1126 CDD:285248
EGF_2 <1135..1157 CDD:285248
EGF_CA 1163..1192 CDD:238011
NHL 1622..1927 CDD:302697
NHL repeat 1675..1721 CDD:271320
NHL repeat 1745..1787 CDD:271320
NHL repeat 1802..1847 CDD:271320
NHL repeat 1864..1897 CDD:271320
RHS_repeat 2213..2250 CDD:283287
RhsA 2397..2958 CDD:225750
Rhs_assc_core 2939..3015 CDD:274730
Tox-GHH 3274..3349 CDD:292269
TNNXP_016857537.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1225
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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