Protein Alignment CG1924 and CANX

DIOPT Version :10

• Sequence 1: NP_572788.2
• Gene: CG1924 / 32180
• FlyBaseID: FBgn0030377
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_001350922.1
• Gene: CANX / 821
• HGNCID: 1473
• Length: 646
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 250/528 - (47%)
• Similarity: 328/528 - (62%)
• Gaps: 43/528 - (8%)

  Fly    13 LSMLFASSLLLLSAVKAIDSDLEWDDFEDVDVEDVQQEDVDEKP-----------TYKSPVIDAK 66
            |.||......::.|....|.|:  .|.|| |::||.:|..|.||           |||:|| ...
Human    61 LCMLLVLGTAIVEAHDGHDDDV--IDIED-DLDDVIEEVEDSKPDTTAPPSSPKVTYKAPV-PTG 121

  Fly    67 KFHFADHFDDMEASTRRWVLSQAKKDDIADEISKYDGIWNWEPPQRMVWANDLGLVLKSKAKHAA 131
            :.:|||.||  ..:...|:||:|||||..|||:||||.|..|..:......|.||||.|:|||.|
Human   122 EVYFADSFD--RGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHA 184

  Fly   132 IAAHLHQPFDFKSEKPLVVQYEITIQKGQECGGSYLKLLSAGKETEQLQTFNDKTPYTIMFGPDK 196
            |:|.|::||.|.: |||:||||:..|.|.||||:|:||||...|. .|..|:|||||||||||||
Human   185 ISAKLNKPFLFDT-KPLIVQYEVNFQNGIECGGAYVKLLSKTPEL-NLDQFHDKTPYTIMFGPDK 247

  Fly   197 CGKDVTIHFIFKHVNPINGTITEKHCNKPNNSFEEPFKDKLPHLYQLVVRPDNSFEIRIDHKIIK 261
            ||:|..:||||:|.||..|...|||..:|:...:..|.||..|||.|::.|||||||.:|..::.
Human   248 CGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVN 312

  Fly   262 EGSLLTDFKPPVNPPAEIDDPNDHKPDSWDEREKIPDPTVHKPEDWDENETLKLPD--------- 317
            .|:||.|..|||||..||:||.|.||:.||||.|||||...||:||||:...|:||
Human   313 SGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGW 377

  Fly   318 ----ADMIFDPTATKPEDWDDEIDGEWQAPMVDNPVCKKDQTCG-----IIRNPNYKGKWIAPMI 373
                .:.:.||.|.||||||:::||||:||.:.||.|:....||     :|.||||||||..|||
Human   378 LDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMI 442

  Fly   374 DNPNYQGKWAPRKIANPDFFEDLKPFQMTPISAVGLELWSMSSDILFDNLIITDDVEVARDFAAN 438
            |||:|||.|.||||.||||||||:||:|||.||:|||||||:|||.|||.||..|..:..|:|.:
Human   443 DNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWAND 507

  Fly   439 SFDIKRRYIDRERDSIVNKVVELVKDYPSIWAIGL--VAIVALVALTKCCRFGTTKIQESAAAES 501
            .:.:|:.........:|.:::|..::.|.:|.:.:  ||:...:.:..||    :..::::..|.
Human   508 GWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCC----SGKKQTSGMEY 568

  Fly   502 KKTDDPQP 509
            ||||.|||
Human   569 KKTDAPQP 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1924	NP_572788.2	Calreticulin	70..425	CDD:459737	207/372 (56%)
CANX	NP_001350922.1	Calreticulin	125..494	CDD:459737	207/372 (56%)