Protein Alignment CG1924 and cnx-1

DIOPT Version :10

• Sequence 1: NP_572788.2
• Gene: CG1924 / 32180
• FlyBaseID: FBgn0030377
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_499176.1
• Gene: cnx-1 / 176390
• WormBaseID: WBGene00000567
• Length: 619
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 226/603 - (37%)
• Similarity: 331/603 - (54%)
• Gaps: 90/603 - (14%)

  Fly    22 LLLSAVKAIDSDLEWDDFEDVDVEDVQQEDVDEKPTYKSPVIDAKKF------HFADHFDDMEAS 80
            ||:|::::.|     |.||| |.|:|.:.. |:|..:...:..|.|.      :|.|:|......
 Worm    14 LLVSSIRSDD-----DVFED-DEEEVTKGS-DDKEEFVPSLFVAPKLSDKSTPNFFDYFPVGSKI 71

  Fly    81 TRRWVLSQAKKDDIADEISKYDGIWNWEPPQRMVWANDLGLVLKSKAKHAAIAAHLHQPFDFKSE 145
            ...|:.|.|||||:..:|:||:|.|:...|.::....||||::|:||:|.||||.|:.||.|.:
 Worm    72 GLTWIKSLAKKDDVDSDIAKYNGEWSIGAPTKVSIEGDLGLIVKTKARHHAIAAKLNTPFAFDA- 135

  Fly   146 KPLVVQYEITIQKGQECGGSYLKLLSAGKETEQLQTFNDKTPYTIMFGPDKCGKDVTIHFIFKHV 210
            ...||||:|..::||||||.||||||.|.| :.|..|.|||.|||||||||||....:|.||::.
 Worm   136 NTFVVQYDIKFEEGQECGGGYLKLLSEGAE-KDLANFQDKTAYTIMFGPDKCGATGKVHLIFRYK 199

  Fly   211 NPINGTITEKHCNKPNNSFEEPFKDKLPHLYQLVVRPDNSFEIRIDHKIIKEGSLLTDFKPPVNP 275
            |||||||:|.|.|:|.......:.|...||:.|||:|...:.:.:|.|.:..|::::|..|.:.|
 Worm   200 NPINGTISEYHANQPTTIGSTYWDDHNTHLFTLVVKPTGEYSVSVDGKSLYYGNMMSDVTPALTP 264

  Fly   276 PAEIDDPNDHKPDSWDEREKIPDPTVHKPEDWDENETLKLPDA-------------DMIFDPTAT 327
            |.:|.|..|.||..|||||.|.|.:..||:||||||...:.|.             ::|.||.|.
 Worm   265 PKQIFDETDLKPVDWDERENIEDESAVKPDDWDENEPQSVVDEAATKPYDWNEEENELIADPEAK 329

  Fly   328 KPEDWDDEIDGEWQAPMVDNPVCKKDQTCG-----IIRNPNYKGKWIAPMIDNPNYQGKWAPRKI 387
            ||:|||:::||.|:||::|||.||....||     .|:||.||||||.|.|.||.::|||..|.|
 Worm   330 KPQDWDEDMDGSWEAPLIDNPACKGLSGCGTWKAPTIKNPKYKGKWIRPKISNPAFKGKWTARLI 394

  Fly   388 ANPDFFEDLKPFQ-MTPISAVGLELWSMSSDILFDNLIITDDVEVARDFAANSFDIKRRYIDR-- 449
            .||::||. |||. :.||:|||:|:|:||.:|||||::||...|.:.|.|..:|.:|::...|
 Worm   395 DNPNYFEP-KPFAGLAPITAVGIEMWTMSENILFDNILITSSEEDSSDVAKQTFYVKQKEEYRLA 458

  Fly   450 ----ERDSIVNKVVELVKDYPSIWAIGLVAI-VALVALTKCCRFGT--------TKIQESAAAES 501
                ..:....::::...:.|.:||:.::.: :.|||:...| ||.        .|..::.:|:.
 Worm   459 AATGNGNGFFQQIIDATNEKPWLWAVYILCVLLPLVAIGVFC-FGKQSKPTPNFAKKSDAYSADD 522

  Fly   502 KKT-----DDPQP---------HEPRPWGSRMSRAKKWKLTIPPRRAYSCPLPPKKKLDDNEWKF 552
            .:.     ||.:.         ::|.|.||:                 |.|.|     .|.|
 Worm   523 DRVPNLVDDDEEEIIGDEEDDVNQPGPSGSQ-----------------SNPEP-----QDEE--- 562

  Fly   553 KAAKKQKHTQTKESNTEE 570
            :.|::|....::.|..||
 Worm   563 ENAEQQSANSSQSSAAEE 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1924	NP_572788.2	Calreticulin	70..425	CDD:459737	176/373 (47%)
cnx-1	NP_499176.1	Calreticulin	62..432	CDD:459737	175/372 (47%)