DRSC/TRiP Functional Genomics Resources

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Protein Alignment HOXB8 and ftz

DIOPT Version :9

Sequence 1:NP_076921.1 Gene:HOXB8 / 3218 HGNCID:5119 Length:243 Species:Homo sapiens
Sequence 2:NP_477498.1 Gene:ftz / 40834 FlyBaseID:FBgn0001077 Length:410 Species:Drosophila melanogaster


Alignment Length:195 Identity:67/195 - (34%)
Similarity:89/195 - (45%) Gaps:70/195 - (35%)


- Green bases have known domain annotations that are detailed below.


Human    39 VYGPSSGGSFQHPSQIQEFYHG---------PSSL------STAPYQQNPCAVACHGDPGNFYGY 88
            ||.|.        ||.|:..:|         |:||      ||.|  |:|               
  Fly   173 VYSPQ--------SQTQKLKNGDFATPPPTTPTSLPPLEGISTPP--QSP--------------- 212

Human    89 DPLQRQSLFGAQDPDLV-QYADCKLAAA-SGLGEEAEGSEQSPSPTQLFPWMRPQAAAG-----R 146
                     |.:....| |..:.::..| :|.|:              |.|...:....     .
  Fly   213 ---------GEKSSSAVSQEINHRIVTAPNGAGD--------------FNWSHIEETLASDCKDS 254

Human   147 RRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFP 211
            :|.||||:|||||||||||.||.|:||:|||::::||.|:|||:||||||||||.||:...|..|
  Fly   255 KRTRQTYTRYQTLELEKEFHFNRYITRRRRIDIANALSLSERQIKIWFQNRRMKSKKDRTLDSSP 319

Human   212  211
              Fly   320  319

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HOXB8NP_076921.1 Antp-type hexapeptide 134..139 2/4 (50%)
Homeobox 150..203 CDD:395001 39/52 (75%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 203..243 3/9 (33%)
ftzNP_477498.1 FTZ 1..248 CDD:281812 23/122 (19%)
Homeobox 257..310 CDD:278475 39/52 (75%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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