Protein Alignment HOXB8 and Scr

DIOPT Version :9

• Sequence 1: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Sequence 2: NP_001368995.1
• Gene: Scr / 40833
• FlyBaseID: FBgn0003339
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 228
• Identity: 84/228 - (36%)
• Similarity: 104/228 - (45%)
• Gaps: 65/228 - (28%)

Human     7 NSLFSKYKTGESLRPNYYDCGFAQDLGGR---PTVVYGPSS--------------GGSFQHPSQI 54
            ||..|.....:||       ...|||..|   |.:  .|||              |||.
  Fly   192 NSANSNNNNSQSL-------ASPQDLSTRDISPKL--SPSSVVESVARSLNKGVLGGSL------ 241

Human    55 QEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLG 119
                  .::.:.|....|.......|.|||.  ..|:...   |..|.|          :.|..|
  Fly   242 ------AAAAAAAGLNNNHSGSGVSGGPGNV--NVPMHSP---GGGDSD----------SESDSG 285

Human   120 EEAEGSEQS----PSPTQLFPWMR--------PQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLT 172
            .||..|:.|    .:|.|::|||:        ..|....:|.|.:|:|||||||||||.||.|||
  Fly   286 NEAGSSQNSGNGKKNPPQIYPWMKRVHLGTSTVNANGETKRQRTSYTRYQTLELEKEFHFNRYLT 350

Human   173 RKRRIEVSHALGLTERQVKIWFQNRRMKWKKEN 205
            |:||||::|||.|||||:||||||||||||||:
  Fly   351 RRRRIEIAHALCLTERQIKIWFQNRRMKWKKEH 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		2/4 (50%)
		Homeobox	150..203	CDD:395001	42/52 (81%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		2/3 (67%)
Scr	NP_001368995.1	Homeobox	328..381	CDD:395001	42/52 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.810