DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HOXB8 and zen2

DIOPT Version :9

Sequence 1:	NP_076921.1	Gene:	HOXB8 / 3218	HGNCID:	5119	Length:	243	Species:	Homo sapiens
Sequence 2:	NP_476794.1	Gene:	zen2 / 40827	FlyBaseID:	FBgn0004054	Length:	252	Species:	Drosophila melanogaster

Alignment Length:	160	Identity:	56/160 - (35%)
Similarity:	71/160 - (44%)	Gaps:	40/160 - (25%)

- Green bases have known domain annotations that are detailed below.

Human   103 DLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLF 167
            ||:.|...:|...:........||:|                  :|.|..:|..|.:|||:||..
  Fly    18 DLMMYPCVELNVEAAPTATTRSSEKS------------------KRSRTAFSSLQLIELEREFHL 64

Human   168 NPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNK--------DKFPSSKCEQEELEKQ- 223
            |.||.|.||||:|..|.||||||||||||||||.||..|:        ...|.|....|:|:|.
  Fly    65 NKYLARTRRIEISQRLALTERQVKIWFQNRRMKLKKSTNRKGAIGALTTSIPLSSQSSEDLQKDD 129

Human   224 ------------KLERAP-EAADEGDAQKG 240
                        .:|.|| ...|.|..::|
  Fly   130 QIVERLLRYANTNVETAPLRQVDHGVLEEG 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		0/4 (0%)
		Homeobox	150..203	CDD:395001	34/52 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	203..243		13/60 (22%)
zen2	NP_476794.1	Homeobox	46..99	CDD:278475	34/52 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810