Protein Alignment CG11356 and ARL13B

DIOPT Version :10

• Sequence 1: NP_572786.3
• Gene: CG11356 / 32178
• FlyBaseID: FBgn0030375
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_878899.1
• Gene: ARL13B / 200894
• HGNCID: 25419
• Length: 428
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 57/248 - (22%)
• Similarity: 110/248 - (44%)
• Gaps: 47/248 - (18%)

  Fly    19 SCC----RTSSPAMEEFQVLILGPSGSGKTELGHRLSRVSRDRDDQEATNGVRCYRMKSAEEPIA 79
            |||    |...| :.:..:|::|...:|||.....:.  ....:|...|.|.....::..:   .
Human     7 SCCGWFKRWREP-VRKVTLLMVGLDNAGKTATAKGIQ--GEYPEDVAPTVGFSKINLRQGK---F 65

  Fly    80 QLQLTEVGGNVEMQRLWKHYYASSHALIYCFDLGADPMVMQGTFSLLTDCLVGTQLAGKPVLLVA 144
            ::.:.::||.:.::.:||:|||.|:.:|:..| .:|...|:.|...:::.|...:::|||:|::|
Human    66 EVTIFDLGGGIRIRGIWKNYYAESYGVIFVVD-SSDEERMEETKEAMSEMLRHPRISGKPILVLA 129

  Fly   145 SRHRVGVQLYDVEYAFG---------LEELAKSCDCPLLICHMDE-----------TEDLHRGIR 189
            ::.       |.|.|.|         ||:|.....|   :|.::.           .:.:.:|:.
Human   130 NKQ-------DKEGALGEADVIECLSLEKLVNEHKC---LCQIEPCSAISGYGKKIDKSIKKGLY 184

  Fly   190 WLCHQLMARKSQLDQRIRYDVNMQVWQRRKRSLLPSAKLAQVHRHRFRRQTRK 242
            ||.|.:......|::||:.:...|      |:|....|..:..|.|..|:.||
Human   185 WLLHVIARDFDALNERIQKETTEQ------RALEEQEKQERAERVRKLREERK 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11356	NP_572786.3	P-loop containing Nucleoside Triphosphate Hydrolases	32..194	CDD:476819	39/181 (22%)
ARL13B	NP_878899.1	Arl2l1_Arl13_like	23..189	CDD:133361	39/181 (22%)
		CCDC47	<199..241	CDD:480722	11/39 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	207..287		9/31 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..428