DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uch-L5R and Uch-L5

DIOPT Version :9

Sequence 1:	NP_572781.1	Gene:	Uch-L5R / 32173	FlyBaseID:	FBgn0030370	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001261632.1	Gene:	Uch-L5 / 39102	FlyBaseID:	FBgn0011327	Length:	324	Species:	Drosophila melanogaster

Alignment Length:	319	Identity:	199/319 - (62%)
Similarity:	255/319 - (79%)	Gaps:	6/319 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 ANNWCLIESDPGVFTEMISGFGCTGAEVEEIWSIKADAFRHLEPIHGLIFLFKWL-DDKPAGRVV 85
            |.||||||||||||||:|..|||.||:||||||:.:::|::|||||||||||||: :|:|||:||
  Fly     5 AGNWCLIESDPGVFTELIREFGCDGAQVEEIWSLDSESFKNLEPIHGLIFLFKWVQEDEPAGKVV 69

  Fly    86 TDRSDIFFARQVIPNACATQALLCLLLNLQHEDIDLGQTLTDLRNLCQDLDPECRGHRLANEEKI 150
            .||.:||||:|||.|||||||:|.||:||.||||.||:|||:.:..||..||..:|..|:|..:|
  Fly    70 LDRENIFFAKQVINNACATQAILSLLMNLDHEDIKLGETLTNFKEFCQCFDPYNKGLTLSNASQI 134

  Fly   151 RKVHNSFARPELFVVEESTDFIEDDCYHFVGFMPIKGKLFELDGMHEGPIELADIDQQQNWLDVV 215
            |.||||||||.||.::......:||.|||||:|||.|:|:||||:.||||:|.:|..:|||:|||
  Fly   135 RTVHNSFARPTLFELDTKNQKKDDDVYHFVGYMPIGGRLYELDGLREGPIDLGEIKSEQNWIDVV 199

  Fly   216 RPIIEARMERYSVGEIHFNLMALVSDRQRCYERKIQMLVN-LPSQL-SHADRQAEIANLRSHVRH 278
            |||||.||:|||.||||||||||:|||||.||::|:.|:| .|:.: :..||||||::||:::.:
  Fly   200 RPIIEKRMQRYSDGEIHFNLMALISDRQRIYEQQIEKLLNPAPNAMDTEEDRQAEISSLRTYIEY 264

  Fly   279 EKEKKRRYRKENIRRRHNYLPFIVELLKQLGETGQLMAICDKAKDRSY---LCKPSKDT 334
            |.:||:||:.||:||:||||||||||||.|||.||||.|.:|||.|:.   ..:..|||
  Fly   265 EIQKKKRYKVENVRRKHNYLPFIVELLKILGENGQLMPIYEKAKQRALEREQAQRKKDT 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uch-L5R	NP_572781.1	Peptidase_C12_UCH37_BAP1	25..238	CDD:187738	140/213 (66%)
Uch-L5	NP_001261632.1	Peptidase_C12_UCH37_BAP1	8..222	CDD:187738	140/213 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469756
Domainoid	1	1.000	212	1.000	Domainoid score	I779
eggNOG	1	0.900	-	-		E1_KOG2778
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	287	1.000	Inparanoid score	I846
Isobase	1	0.950	-	0	Normalized mean entropy	S1802
OMA	1	1.010	-	-		QHG53985
OrthoDB	1	1.010	-	-		D1363547at2759
OrthoFinder	1	1.000	-	-		FOG0001783
OrthoInspector	1	1.000	-	-		otm25930
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10589
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1589
SonicParanoid	1	1.000	-	-		X1137
	13	12.890