DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp318a1 and CYP72A7

DIOPT Version :9

Sequence 1:	NP_727590.1	Gene:	Cyp318a1 / 32172	FlyBaseID:	FBgn0030369	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_188079.1	Gene:	CYP72A7 / 820689	AraportID:	AT3G14610	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	581	Identity:	123/581 - (21%)
Similarity:	225/581 - (38%)	Gaps:	143/581 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ACGALLAVLLAWQQRKCWRL---IW----------QLNGWRGVIQQPVLW-------LLLCINLH 53
            |...|:||::.|    .||:   :|          :..|..|....|::.       :::.....
plant     8 ALPVLVAVVVLW----TWRIVKWVWIKPKMLESSLKRQGLTGTPYTPLVGDIKRNVDMMMEARSK 68

  Fly    54 PNSILEKVSQYRVHFQRPLA------------VLVGTRVLLYIDDPAGMECVLNAPECLDK--TF 104
            |.::.:.::...:    |||            :.:|....:.|.:|..::.|.|.....:|  ||
plant    69 PINVTDDITPRLL----PLALKMLNSHGKTFFIWIGPLPTIVITNPEQIKEVFNKVNDFEKASTF 129

  Fly   105 ----LQDGFFVRRGLLHARGQKWKLRRKQLNPAFS----HNIVASFFDVFNSVGNQMVEQF---- 157
                |..|     ||...:|.||...|:.:||||.    .|::.:|:...:.|..|..:.|
plant   130 PLIRLLAG-----GLASYKGDKWASHRRIINPAFHLEKIKNMIPAFYHCCSEVVCQWEKLFTDKE 189

  Fly   158 -QTQTNLHGQAVKFTAAEDLLSRAVLEVSCLTIMGTPTNFTQLDDAHIAHSYK----------RL 211
             ..:.::....|..||  |::|.        |..|:              |||          .|
plant   190 SPLEVDVWPWLVNMTA--DVISH--------TAFGS--------------SYKEGQRIFQLQGEL 230

  Fly   212 LEISAVRVVKPWLQIRLLHRLLAPELYEESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGE 276
            .|:.|....|.::.   ..|....:.....|...:.::..:.|||..:.   :.|:|  ||.:.:
plant   231 AELIAQAFKKSYIP---GSRFYPTKSNRRMKAIDREVDVILRGIVSKRE---KAREA--GEPAND 287

  Fly   277 DASNGWQRRIFIEQIFQLAANGEMTLEEIMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQRR 341
            |...     |.:|...:.:....|::|::|.|.:.......||.|..::..::.|:.:: |.|.|
plant   288 DLLG-----ILLESNSEESQGNGMSVEDVMKECKLFYFAGQETTSVLLVWTMVLLSHHQ-DWQAR 346

  Fly   342 LLAEIRALVPDVGQVGLEQLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLAGRQHETIVPQN 406
            ...|:..::.:..:..:|.|..|:.:....:|.|||...|....|.|:::.:|.    |..:|..
plant   347 AREEVMQVLGENNKPDMESLNNLKVMTMIFNEVLRLYPPVAQLKRVVNKEMKLG----ELTLPAG 407

  Fly   407 SIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFS 471
            ..:.|.|..:|||...||.:|..|.|:||.|    .|||.              .::..||.||.
plant   408 IQIYLPTILVQRDTELWGDDAADFKPERFRD----GLSKA--------------TKNQVSFFPFG 454

  Fly   472 NGLRSCIGRRYGLFIMKVFLVKLITNFDFQSDFELEKLQFVENISLKFKNADDILLTIQPK 532
            .|.|.|||:.:.:...|:.:..::..|.|:             :|..:.:|...::|.:|:
plant   455 WGPRICIGQNFAMLEAKMAMALILQKFSFE-------------LSPSYVHAPQTVMTTRPQ 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	p450	42..503	CDD:299894	109/504 (22%)
CYP72A7	NP_188079.1	p450	21..512	CDD:299894	118/564 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870