DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Cyp318a1 and BAS1

DIOPT Version :9

Sequence 1:NP_727590.1 Gene:Cyp318a1 / 32172 FlyBaseID:FBgn0030369 Length:536 Species:Drosophila melanogaster
Sequence 2:NP_180239.1 Gene:BAS1 / 817212 AraportID:AT2G26710 Length:520 Species:Arabidopsis thaliana


Alignment Length:586 Identity:110/586 - (18%)
Similarity:228/586 - (38%) Gaps:161/586 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 LLAVLLAWQQRKCWRLIWQLNGWR-----------GVIQQP----------VLWLLLCINLHP-- 54
            :|:|:|:....|...|:|    ||           |:...|          ::.::|..:.||  
plant    15 VLSVILSLVIVKGMSLLW----WRPRKIEEHFSKQGIRGPPYHFFIGNVKELVGMMLKASSHPMP 75

  Fly    55 --NSILEKVSQYRVHFQRPLAVLVGTRVLLYIDDPAGMECVLNAPECLDKTFLQDGFFVRR---- 113
              ::||.:|..:..|:::    :.|...|::....  ....:..|:.:.:.|.:..|:.:.    
plant    76 FSHNILPRVLSFYHHWRK----IYGATFLVWFGPT--FRLTVADPDLIREIFSKSEFYEKNEAHP 134

  Fly   114 --------GLLHARGQKWKLRRKQLNPAFSHN--------IVASFFDVFNSVGNQMVEQFQTQTN 162
                    |||..:|:||...||.::|.|...        ::.|..|:.:...:::.|..:.:.:
plant   135 LVKQLEGDGLLSLKGEKWAHHRKIISPTFHMENLKLLVPVVLKSVTDMVDKWSDKLSENGEVEVD 199

  Fly   163 LHGQAVKFTAAEDLLSRAVLEVSCLTIMGTPTNFTQLDDAHIAHSYKRLLEISAVRVVKPWLQIR 227
            ::......|  ||::||        |..|:              ||:               ..|
plant   200 VYEWFQILT--EDVISR--------TAFGS--------------SYE---------------DGR 225

  Fly   228 LLHRLLAPELYEESKKCAKLLED-FVGGI----VRTKHRNWRL----------------RDAVGG 271
            .:.||.|.::.    .||:..:. |:.|.    .|...::|:|                ::|:.|
plant   226 AVFRLQAQQML----LCAEAFQKVFIPGYRFFPTRGNLKSWKLDKEIRKSLLKLIERRRQNAIDG 286

  Fly   272 EKSGEDASNGWQRRIFIEQIFQLAANGEMTLEEIMDEAQSMVLVSFETVSNSIMLALLCLATNKG 336
            |  ||:......:.:.  .:...|.|  :|:::|::|.:|......:|.||.:....:.|:.:. 
plant   287 E--GEECKEPAAKDLL--GLMIQAKN--VTVQDIVEECKSFFFAGKQTTSNLLTWTTILLSMHP- 344

  Fly   337 DCQRRLLAEIRALVPDVGQVGLEQLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLAGRQHET 401
            :.|.:...|:..:.........:.:.:|:.|...::|||||...:...:|....|.:|.|.:   
plant   345 EWQAKARDEVLRVCGSRDVPTKDHVVKLKTLSMILNESLRLYPPIVATIRRAKSDVKLGGYK--- 406

  Fly   402 IVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYS 466
             :|..:.:::....:..|:..||.:..:|:|.||.|..                  .|..:|...
plant   407 -IPCGTELLIPIIAVHHDQAIWGNDVNEFNPARFADGV------------------PRAAKHPVG 452

  Fly   467 FLPFSNGLRSCIGRRYGLFIMKVFLVKLITNFDFQSDFELEKLQFVENISLKFKNADDILLTIQP 531
            |:||..|:|:|||:...:...|:.|..:|..|.|             :::..:::|..:|:.:.|
plant   453 FIPFGLGVRTCIGQNLAILQAKLTLAVMIQRFTF-------------HLAPTYQHAPTVLMLLYP 504

  Fly   532 K 532
            :
plant   505 Q 505

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp318a1NP_727590.1 p450 42..503 CDD:299894 98/515 (19%)
BAS1NP_180239.1 CYP734 85..509 CDD:410732 94/512 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
21.870

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