DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp318a1 and zgc:123299

DIOPT Version :9

Sequence 1:	NP_727590.1	Gene:	Cyp318a1 / 32172	FlyBaseID:	FBgn0030369	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	XP_021324190.1	Gene:	zgc:123299 / 641477	ZFINID:	ZDB-GENE-051120-33	Length:	501	Species:	Danio rerio

Alignment Length:	484	Identity:	113/484 - (23%)
Similarity:	206/484 - (42%)	Gaps:	88/484 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 YRVHFQRPLAVLV----GTRVLL----YIDDPAGMECVLNAPECLDKTFLQDGFFVRRGLLHARG 120
            ||::....:.::|    .|:.::    |..||.....|.|   ...|.||  |:    ||:.|..
Zfish    80 YRINTLHYVTIVVYCPEATKTIMMSPKYTKDPFVYRRVFN---LFGKRFL--GY----GLITAVD 135

  Fly   121 QK-WKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVLEV 184
            .. |..:|:.::||||.:.:.|....|:.:..:::::.:...|....||    ..||::...|:|
Zfish   136 HDIWYRQRRIMDPAFSSSYLRSLISTFDEMSERLMDKLEEIANNKTPAV----MHDLVNCVTLDV 196

  Fly   185 SCLTIMGTPTNFTQLDDAHIAHSYKRLLEISAVRVVKPWLQIRLLHRLLAP--ELYEESKKCAKL 247
            .|....|...||....|:...::.:..|:.....|..|      |.|::..  :|.::.::..:|
Zfish   197 ICKVAFGVDLNFLTQKDSPFQNAVELCLKGMTFDVRDP------LFRIIPKNWKLIQQVREATEL 255

  Fly   248 LEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRIFIEQIFQLAANGEMT----LEEIMDE 308
            |        |.....| :::.....|:|||..     :..:.||.:.|....:|    .|:::|.
Zfish   256 L--------RKTGEKW-IQNRKTAVKNGEDVP-----KDILTQILKSAEEQNVTSTEDFEQMLDN 306

  Fly   309 AQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLEQLQQLRYLDAFVSE 373
            ..:..:...||.:|.:..|::.|..|. :..:|..||:..::....::..|.|.:|.||...:.|
Zfish   307 FVTFFMAGQETTANQLSFAIMELGRNP-EIYKRAKAEVDEVLGTKREISNEDLGKLTYLSQVLKE 370

  Fly   374 SLRLLATVPMNLRHVSRDFRLAGRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQ 438
            :|||..|.|...|.:..|..:.|.:    :|....|:.::|..||.|::: .:..:|||:||
Zfish   371 TLRLYPTAPGTNRWLHEDMIINGIK----IPGGCSVMFNSFVSQRLEKFF-KDPLKFDPKRF--- 427

  Fly   439 EEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNFDFQSD 503
             :|...|.:                 |::.||:.|.|:|||:.:.....||.|.||:..|:|
Zfish   428 -DENAPKPY-----------------YTYYPFALGPRTCIGQVFSQMEAKVVLAKLLQRFEF--- 471

  Fly   504 FELEKLQFVENISLKFKNADDILLTIQPK 532
                  ..|...|...|:..    |::||
Zfish   472 ------SLVPGQSFDIKDTG----TLRPK 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	p450	42..503	CDD:299894	107/453 (24%)
zgc:123299	XP_021324190.1	p450	39..495	CDD:306555	113/484 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010