Protein Alignment Cyp318a1 and CYP4F11

DIOPT Version :9

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001122404.1
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 551
• Identity: 129/551 - (23%)
• Similarity: 220/551 - (39%)
• Gaps: 156/551 - (28%)

  Fly    13 LLAVLLAWQQR---KCWRL-----------IWQLNGWRGVI------------------QQPVLW 45
            |||.:|||...   .|.||           .|   |.:|::                  |...||
Human    30 LLARVLAWTYTFYDNCRRLQCFPQPPKQNWFW---GHQGLVTPTEEGMKTLTQLVTTYPQGFKLW 91

  Fly    46 -------LLLCINLHPNSILEKVSQYRVHFQRPL----AVLVGTRVLLYIDDPAGMECVLNAPEC 99
                   |:||   ||:.|            ||:    |.:....::.|
Human    92 LGPTFPLLILC---HPDII------------RPITSASAAVAPKDMIFY---------------- 125

  Fly   100 LDKTFLQDGF---FVRRGLLHARGQKWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQT 161
                    ||   ::..|||.:.|.||...|:.|.|||..||:..:..:||...|.|.:::|.
Human   126 --------GFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR-- 180

  Fly   162 NLHGQAVKFTAAEDLLSRAVLEVSCLT-------IMGTPTNFTQLDDAHIAHSYKRLLEISAVRV 219
                .|.:.:|..|:..    .:|.:|       :....:|..:....:||    .:||:||. |
Human   181 ----LASEGSARLDMFE----HISLMTLDSLQKCVFSFESNCQEKPSEYIA----AILELSAF-V 232

  Fly   220 VKPWLQIRLLHR----LLAPELYEESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASN 280
            .|...|| |||.    .|.|: .:..::...|:.||...:::.:      |..:..:...:...|
Human   233 EKRNQQI-LLHTDFLYYLTPD-GQRFRRACHLVHDFTDAVIQER------RCTLPTQGIDDFLKN 289

  Fly   281 GWQRRI--FIEQIFQLAAN---GEMTLEEIMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQR 340
            ..:.:.  ||: :..|:.:   .|::.|:|..||.:.:....:|.::.:...|..||.:. :.|.
Human   290 KAKSKTLDFID-VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHP-EYQE 352

  Fly   341 RLLAEIRALVPDVGQVGLE--QLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLA-GRQHETI 402
            :...|::.|:.|...:.:|  .|.||.:|...:.|||||...||:..|..::||.|. ||    :
Human   353 QCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGR----V 413

  Fly   403 VPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSF 467
            :|:..:.:::...:..:...| .:...:||.|| |||..:                  .|...:|
Human   414 IPKGIVCLINIIGIHYNPTVW-PDPEVYDPFRF-DQENIK------------------ERSPLAF 458

  Fly   468 LPFSNGLRSCIGRRYGLFIMKVFLVKLITNF 498
            :|||.|.|:|||:.:.:..|||.|...:.:|
Human   459 IPFSAGPRNCIGQAFAMAEMKVVLALTLLHF 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	p450	42..503	CDD:299894	116/490 (24%)
CYP4F11	NP_001122404.1	p450	52..506	CDD:365848	120/529 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820