Protein Alignment Cyp318a1 and Cyp4a12a

DIOPT Version :10

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_803125.2
• Gene: Cyp4a12a / 277753
• MGIID: 88612
• Length: 508
• Species: Mus musculus
• Alignment Length: 534
• Identity: 123/534 - (23%)
• Similarity: 216/534 - (40%)
• Gaps: 120/534 - (22%)

  Fly    30 WQLNGWRGVIQQPVLWLL---LCINLHPNSILEKVSQYRVHFQRPLAV---LVGTRVLLYIDDPA 88
            |.|:..:.....|..||.   :..:.....||.::..:      |.|.   |.|::|.:.:.||.
Mouse    43 WLLSSTQQFPSPPSHWLFGHKILKDQDLQDILTRIKNF------PSACPQWLWGSKVRIQVYDPD 101

  Fly    89 GMECVLN-------------APECLDKTFLQDGFFVRRGLLHARGQKWKLRRKQLNPAFSHNIVA 140
            .|:.:|.             ||            ::.||||...||.|...|:.|.|||.::|:.
Mouse   102 YMKLILGRSDPKANGSYRFLAP------------WIGRGLLMLDGQTWFQHRRMLTPAFHYDILK 154

  Fly   141 SFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVLEV-SCLTIMGTPT----NFTQLD 200
            .:.::.......|:::::   .:.||            .:.||: ..:|:|...|    .|:...
Mouse   155 PYTEIMADSVRVMLDKWE---QIVGQ------------DSTLEIFRHITLMTLDTIMKCAFSHEG 204

  Fly   201 DAHIAHSYKRLLE---------ISAVRVVKPWLQIRLLHRLLAPELYEESKKC-----AKLLEDF 251
            ...:...||..::         .|.||.:  :.|..:::|:       .|..|     .||..|.
Mouse   205 SVQLDRKYKSYIQAVEDLNDLVFSRVRNI--FHQNDIIYRV-------SSNGCKANSACKLAHDH 260

  Fly   252 VGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRI-FIE-QIFQLAANGE-MTLEEIMDEAQSMV 313
            ...::  |.|..:|:|....||..:      :||: |:: .:|....||: ::.:::..|..:.:
Mouse   261 TDQVI--KSRRIQLQDEEELEKLKK------KRRLDFLDILLFARMENGKSLSDKDLRAEVDTFM 317

  Fly   314 LVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLEQLQQLRYLDAFVSESLRLL 378
            ....:|.::.|......||||. :.|:|...||::|:.|...:....|.::.|....:.|:||:.
Mouse   318 FEGHDTTASGISWIFYALATNP-EHQQRCRKEIQSLLGDGTSITWNDLDKMPYTTMCIKEALRIY 381

  Fly   379 ATVPMNLRHVSRDFRLA-GRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQ 442
            ..||...|.:|...... ||.    :|:...|:|..:.:..:...| .|...|||.||.
Mouse   382 PPVPSVSRELSSPVTFPDGRS----LPKGIHVMLSFYGLHHNPTVW-PNPEVFDPSRFA------ 435

  Fly   443 LSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNFDFQSDFELE 507
                   .||.        |||:||||||.|.|:|||:::.:..:||.:...:..|:...|....
Mouse   436 -------PGSS--------RHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRV 485

  Fly   508 KLQFVENISLKFKN 521
            .:. :..|.||.||
Mouse   486 PIP-IPRIVLKSKN 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	CYP313-like	69..525	CDD:410680	116/492 (24%)
Cyp4a12a	NP_803125.2	CYP4B-like	70..503	CDD:410771	118/507 (23%)