Protein Alignment Cyp318a1 and Cyp4a8

DIOPT Version :10

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_113793.2
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 508
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 107/499 - (21%)
• Similarity: 202/499 - (40%)
• Gaps: 100/499 - (20%)

  Fly    45 WLLLCINLHPN------------------SILEKVSQYRVHFQRPLAV---LVGTRVLLYIDDPA 88
            |||......|:                  .||.:|..:      |.|.   |.|:.|.:.:.||.
  Rat    43 WLLRATQQFPSPPSHWFFGHKIPKDQEFQDILTRVKNF------PSACPQWLWGSNVRIQVYDPD 101

  Fly    89 GMECVLNAPECLDKTFLQDGF---FVRRGLLHARGQKWKLRRKQLNPAFSHNIVASFFDVFNSVG 150
            .|:.:|...:  .|:.....|   ::..|||...||.|...|:.|.|||.::.:..:..:.....
  Rat   102 YMKLILGRSD--PKSHHSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDTLKPYVGIMADSV 164

  Fly   151 NQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVLEV-SCLTIMGTPT----NFTQLDDAHIAHSYKR 210
            ..|:::::   .:.||            .:.||: ..:|:|...|    .|:|.....:...||.
  Rat   165 RIMLDKWE---QIVGQ------------DSTLEIFQHITLMTLDTIMKCAFSQEGSVQLDRKYKS 214

  Fly   211 LLE-------ISAVRVVKPWLQIRLLHRLLAPELYEESKKCAKLLEDFVGGIVRTKHRNWRLRDA 268
            .::       :|..|:...:.|..:::.|.:..  .:::...:|..:....::  |.|..:|:|.
  Rat   215 YIKAVEDLNNLSFFRIRNIFHQNDIIYSLSSNG--RKARSAWQLAHEHTDQVI--KSRKAQLQDE 275

  Fly   269 VGGEKSGEDASNGWQRRI-FIE-QIFQLAANG-EMTLEEIMDEAQSMVLVSFETVSNSIMLALLC 330
            ...:|..:      :||: |:: .:|....|| .::.:::..|..:.:....:|.::.|......
  Rat   276 EELQKVKQ------KRRLDFLDILLFARIENGSSLSDKDLRAEVDTFMFEGHDTTASGISWIFYA 334

  Fly   331 LATNKGDCQRRLLAEIRALVPDVGQVGLEQLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLA 395
            ||||. :.|:....||::|:.|...:..:.|.::.|....:.|:||:...|....|.:|......
  Rat   335 LATNP-EHQQGCRKEIQSLLGDGASITWDDLDKMPYTTMCIKEALRIYPPVTAVSRMLSTPVTFP 398

  Fly   396 -GRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQR 459
             ||.    :|:...|:|..:.:..:...| .|...|||.||..:..
  Rat   399 DGRS----LPKGITVMLSFYGLHHNPTVW-PNPEVFDPYRFAPESS------------------- 439

  Fly   460 DRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNFDFQSD 503
              |||:||||||.|.|:|||:::.:..:||.:...:..|:...|
  Rat   440 --RHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPD 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	CYP313-like	69..525	CDD:410680	100/457 (22%)
Cyp4a8	NP_113793.2	CYP4B-like	70..503	CDD:410771	103/472 (22%)