Protein Alignment Cyp318a1 and Cyp3a23-3a1

DIOPT Version :10

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 434
• Identity: 104/434 - (23%)
• Similarity: 177/434 - (40%)
• Gaps: 74/434 - (17%)

  Fly   118 ARGQKWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVL 182
            ::.::||..|..|:|.|:...:...|.|....|:.:|:..:.:..      |....:::.....:
  Rat   121 SKDEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQEKG------KPVPVKEVFGAYSM 179

  Fly   183 EVSCLTIMGTPTNFTQLDDAHIAHSYKRLLEISAVRVVKPWLQIRLLHRLLAPELYEESKKC--- 244
            :|...|..|...:.............|:||.|.   ...|.....:|...|.| :||....|
  Rat   180 DVITSTSFGVNVDSLNNPKDPFVEKAKKLLRID---FFDPLFLSVVLFPFLTP-VYEMLNICMFP 240

  Fly   245 AKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRIFIEQIFQLAAN------GEMTLE 303
            ...:|.|...:.|.|..  || |:|            .:.|:...|:...|.|      ....|.
  Rat   241 KDSIEFFKKFVYRMKET--RL-DSV------------QKHRVDFLQLMMNAHNDSKDKESHTALS 290

  Fly   304 EIMDEAQSMVLV--SFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLEQLQQLRY 366
            ::...|||::.:  .:|..|:::...|..|||:. |.|::|..||...:|:......:.:.::.|
  Rat   291 DMEITAQSIIFIFAGYEPTSSTLSFVLHSLATHP-DTQKKLQEEIDRALPNKAPPTYDTVMEMEY 354

  Fly   367 LDAFVSESLRLLATVPMNLRHVSRDFRLAGRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFD 431
            ||..::|:|||........|...:|..:.|    ..:|:.|:|::.::.:.||.:.| ....:|.
  Rat   355 LDMVLNETLRLYPIGNRLERVCKKDVEING----VFMPKGSVVMIPSYALHRDPQHW-PEPEEFR 414

  Fly   432 PQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLIT 496
            |:||..:     :||..|              .|.:|||.||.|:|||.|:.|..||:.|.|::.
  Rat   415 PERFSKE-----NKGSID--------------PYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQ 460

  Fly   497 NFDFQSDFELEKLQFVENISLKFKN------ADDILLTIQPKKE 534
            ||.||...|.:       |.||...      ...|:|.:.|:.|
  Rat   461 NFSFQPCKETQ-------IPLKLSRQGLLQPTKPIILKVVPRDE 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	CYP313-like	69..525	CDD:410680	100/423 (24%)
Cyp3a23-3a1	NP_037237.2	CYP3A	67..491	CDD:410743	101/426 (24%)