Protein Alignment Cyp318a1 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 133/542 - (24%)
• Similarity: 216/542 - (39%)
• Gaps: 119/542 - (21%)

  Fly    45 WLLLCINL--------HPNSILEKVSQYRVHFQRPLAVL-------------------------- 75
            ||||.|:|        |.:.|.:|:.   :...:||..|
  Rat    12 WLLLVISLVLLYLYGTHSHGIFKKLG---IPGPKPLPFLGTILAYRKGFWEFDKYCHKKYGKLWG 73

  Fly    76 --VGTRVLLYIDDPAGMECVLNAPECLDKTFLQDGFFVRRGLLH-----ARGQKWKLRRKQLNPA 133
              .|.:.:|.|.||..::.|| ..||. .||.....|...|:|.     :..::||..|..|:|.
  Rat    74 LYDGRQPVLAITDPDIIKTVL-VKECY-STFTNRRNFGPVGILKKAISISEDEEWKRIRALLSPT 136

  Fly   134 FSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVLEVSCLTIMGTPTNFTQ 198
            |:...:...|.:.|...:.:|...: |.:..|   |.|:.:|:.....::|...|..|...:...
  Rat   137 FTSGKLKEMFPIINQYTDMLVRNMR-QGSEEG---KPTSMKDIFGAYSMDVITATSFGVNVDSLN 197

  Fly   199 LDDAHIAHSYKRLLEISAVRVVKPWLQIRLLHRLLAP--ELYEESKKCAKLLEDFVGGIVRTKHR 261
            ..........|:||:..   :..|......|...|.|  |....|.....:::.|...:.|.|..
  Rat   198 NPQDPFVEKIKKLLKFD---IFDPLFLSVTLFPFLTPLFEALNVSMFPRDVIDFFKTSVERMKEN 259

  Fly   262 NWRLRDAVGGEKSGEDASNGWQRRIFIEQIFQLAANGE--------MTLEEIMDEAQSMVLV--S 316
              |:::.   ||         ||..|:    ||..|.:        ..|.::...|||::.:  .
  Rat   260 --RMKEK---EK---------QRMDFL----QLMINSQNSKVKDSHKALSDVEIVAQSVIFIFAG 306

  Fly   317 FETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLEQLQQLRYLDAFVSESLRLLATV 381
            :||.|:::...|..||.:. |.|::|..||.|.:|:......:.|.|:.|||..|:|:|||....
  Rat   307 YETTSSALSFVLYLLAIHP-DIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYPIA 370

  Fly   382 PMNLRHVSRDFRLAGRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKG 446
            ....|....|..:.|    ..:|:.::|::.||.:.:|..:| ....:|.|:||
  Rat   371 GRLERVCKTDVEING----VFIPKGTVVMIPTFALHKDPHYW-PEPEEFRPERF----------- 419

  Fly   447 HNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNFDFQSDFELEKLQF 511
                    .::.:|..:.|.:|||.||.|:|||.|:.|..|||.||:::.||.||...|.:
  Rat   420 --------SKKNQDNINPYMYLPFGNGPRNCIGMRFALMNMKVALVRVLQNFSFQPCKETQ---- 472

  Fly   512 VENISLKFKNADDILLTIQPKK 533
               |.||.....    .:||:|
  Rat   473 ---IPLKLSKQG----LLQPEK 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	CYP313-like	69..525	CDD:410680	121/500 (24%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	121/484 (25%)