Protein Alignment Cyp318a1 and CYP19A1

DIOPT Version :9

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_000094.2
• Gene: CYP19A1 / 1588
• HGNCID: 2594
• Length: 503
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 84/425 - (19%)
• Similarity: 175/425 - (41%)
• Gaps: 70/425 - (16%)

  Fly   116 LHARG-------QKWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAA 173
            :|.:|       :.||..|.....|.|...:.....|........:::.:..||..|.....|
Human   127 MHEKGIIFNNNPELWKTTRPFFMKALSGPGLVRMVTVCAESLKTHLDRLEEVTNESGYVDVLT-- 189

  Fly   174 EDLLSRAVLEVSCLTIMGTPTNFTQLDDAHIAHSYKRLLEISAVRVVKPWLQIRLLHRLLAPELY 238
              ||.|.:|:.|....:..|     ||::.|....:...:.....::||.:..::      ..||
Human   190 --LLRRVMLDTSNTLFLRIP-----LDESAIVVKIQGYFDAWQALLIKPDIFFKI------SWLY 241

  Fly   239 EESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRIFIEQIFQLAANGEMTLE 303
            ::.:|..|.|:|.:..::..|.|.      :..|:..|:..:      |..::......|::|.|
Human   242 KKYEKSVKDLKDAIEVLIAEKRRR------ISTEEKLEECMD------FATELILAEKRGDLTRE 294

  Fly   304 EIMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLEQLQQLRYLD 368
            .:......|::.:.:|:|.|:...|..:|.:. :.:..::.||:.::.: ..:.::.:|:|:.::
Human   295 NVNQCILEMLIAAPDTMSVSLFFMLFLIAKHP-NVEEAIIKEIQTVIGE-RDIKIDDIQKLKVME 357

  Fly   369 AFVSESLRLLATVPMNLRHVSRDFRLAGRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQ 433
            .|:.||:|....|.:.:|....|..:.|..    |.:.:.::|:...|.|.|.:...|  :|..:
Human   358 NFIYESMRYQPVVDLVMRKALEDDVIDGYP----VKKGTNIILNIGRMHRLEFFPKPN--EFTLE 416

  Fly   434 RFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNF 498
            .|                      .::..:.| |.||..|.|.|.|:...:.:||..||.|:..|
Human   417 NF----------------------AKNVPYRY-FQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458

  Fly   499 DFQS--DFELEKLQFVENISL---KFKNADDILLT 528
            ..::  ...:|.:|.:.::||   :.||..:::.|
Human   459 HVKTLQGQCVESIQKIHDLSLHPDETKNMLEMIFT 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	p450	42..503	CDD:299894	77/395 (19%)
CYP19A1	NP_000094.2	CYP19A1	72..485	CDD:410709	81/415 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010