Protein Alignment Cyp318a1 and CYP4A11

DIOPT Version :9

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_000769.2
• Gene: CYP4A11 / 1579
• HGNCID: 2642
• Length: 519
• Species: Homo sapiens
• Alignment Length: 563
• Identity: 119/563 - (21%)
• Similarity: 202/563 - (35%)
• Gaps: 137/563 - (24%)

  Fly    37 GVIQQPVLWLLLC-------INLHPNSILEKVSQYRV--------HFQR---------------- 70
            |::|...|.:||.       :.||...:|:.:.|:..        |.|.
Human    17 GILQAASLLILLLLLIKAVQLYLHRQWLLKALQQFPCPPSHWLFGHIQELQQDQELQRIQKWVET 81

  Fly    71 -PLAV---LVGTRVLLYIDDPAGMECVLNAPECLDKT-----FLQDGFFVRRGLLHARGQKWKLR 126
             |.|.   |.|.:|.:.:.||..|:.:|...:  .|:     ||..  ::..|||...||.|...
Human    82 FPSACPHWLWGGKVRVQLYDPDYMKVILGRSD--PKSHGSYRFLAP--WIGYGLLLLNGQTWFQH 142

  Fly   127 RKQLNPAFSHNIVASF------------------------FDVFNSVGNQMVEQFQTQTNLHGQA 167
            |:.|.|||.::|:..:                        .:||..|....::........|..:
Human   143 RRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGS 207

  Fly   168 VKFTAAEDLLSRAVLEVSCLTIMGTPTNFTQLDDAHIAHSYKRLLEISAVRVVKPWLQIRLLHRL 232
            ::.........:|:.:::.|........|.|.|..:...|..|            |     .||
Human   208 IQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGR------------W-----THR- 254

  Fly   233 LAPELYEESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRIFIEQIFQLA-- 295
                       ..:|.......:::.:....        :|.||......:|.:....|..||
Human   255 -----------ACQLAHQHTDQVIQLRKAQL--------QKEGELEKIKRKRHLDFLDILLLAKM 300

  Fly   296 ANGE-MTLEEIMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLE 359
            .||. ::.:::..|..:.:....:|.::.|...|..|||:... |.|...||.:|:.|...:...
Human   301 ENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKH-QERCREEIHSLLGDGASITWN 364

  Fly   360 QLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLA-GRQHETIVPQNSIVVLDTFNMQRDERWW 423
            .|.|:.|....:.|:|||...||...|.:|...... ||.    :|:..:|:|..:.:..:.:.|
Human   365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRS----LPKGIMVLLSIYGLHHNPKVW 425

  Fly   424 GANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMK 488
             .|...|||.||.             .||.:        ||::|||||.|.|:|||:::.:..:|
Human   426 -PNPEVFDPFRFA-------------PGSAQ--------HSHAFLPFSGGSRNCIGKQFAMNELK 468

  Fly   489 VFLVKLITNFDFQSDFELEKLQFVENISLKFKNADDILLTIQP 531
            |.....:..|:...|.....:. :..:.||.||...:.|...|
Human   469 VATALTLLRFELLPDPTRIPIP-IARLVLKSKNGIHLRLRRLP 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	p450	42..503	CDD:299894	110/528 (21%)
CYP4A11	NP_000769.2	p450	52..505	CDD:278495	108/521 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820