Protein Alignment Cyp318a1 and Cyp4b1

DIOPT Version :9

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 576
• Identity: 133/576 - (23%)
• Similarity: 224/576 - (38%)
• Gaps: 133/576 - (23%)

  Fly     5 IALWACGALLAVL------LAWQQRKCWRLIWQLNGWRGVIQQPVLWLL-LCINLHPNSILEKVS 62
            :.|||...:|.|.      |.::::|..|.:....|      .|..||. ..:.:.....|:||.
Mouse    13 LGLWASVVILMVTVLKLLSLLFRRQKLARALDSFPG------PPKHWLFGHALEIQKTGGLDKVV 71

  Fly    63 QYRVHFQRPLAVLVGT-RVLLYIDDPAGMECVLNA--PECLDKTFLQDGF--FVRRGLLHARGQK 122
            .:...|.....:.:|. .|.|.|.:|...:.|.:.  |:.   .::.|.|  ::.:|||...|.|
Mouse    72 TWTEQFPYAHPLWLGQFIVFLNIYEPDYAKAVYSRGDPKA---AYVYDFFLQWIGKGLLVLEGPK 133

  Fly   123 WKLRRKQLNPAFSHNI----VASF--------------------FDVFNSVGNQMVEQFQTQTNL 163
            |...||.|.|.|.:::    ||.|                    ||:|..||:..::.....|
Mouse   134 WFQHRKLLTPGFHYDVLKPYVAIFAESTRVMLDKWEKKASENKSFDIFCDVGHMALDTLMKCT-- 196

  Fly   164 HGQAVKFTAAEDLLSRA----VLEVSCLTIMGTPTNFTQLDDAHIAHS---YKRLLEISAVRVVK 221
                  |...:..||.:    .|.||.||::     ..|..|:...|:   |
Mouse   197 ------FGKGDSGLSHSDNSYYLAVSDLTLL-----MQQRIDSFQYHNDFIY------------- 237

  Fly   222 PWLQIRLLHRLLAPELYEESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRI 286
             |         |.|......:.| ::..|....::|  .|...|:|....:|..|      :|.:
Mouse   238 -W---------LTPHGRRFLRAC-QIAHDHTDHVIR--QRKAALQDEKEQKKLQE------RRHL 283

  Fly   287 -FIEQIFQLAANGEMTLE----EIMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEI 346
             |::.:  |.|..|..::    ::..|..:.:....:|.::.|...|.|:|..... |:|...|:
Mouse   284 DFLDIL--LGARDESGIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPMH-QQRCREEV 345

  Fly   347 RALVPDVGQVGLEQLQQLRYLDAFVSESLRLLATVPMNLRHVSRDFRLA-GRQHETIVPQNSIVV 410
            |.::.|......:.|.|:.||...:.|..||...||...|.:|:..... ||.    :|..|::.
Mouse   346 REILGDRDSFQWDDLAQMTYLTMCMKECFRLYPPVPQVYRQLSKPVTFVDGRS----LPAGSLIS 406

  Fly   411 LDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLR 475
            |..:.:.|:...| .:...|||.||..:         |.:|          ||.::|:|||.|.|
Mouse   407 LHIYALHRNSAVW-PDPEVFDPLRFSPE---------NMTG----------RHPFAFMPFSAGPR 451

  Fly   476 SCIGRRYGLFIMKVFLVKLITNFDFQSDFELEKLQFVENISLKFKNADDILLTIQP 531
            :|||:::.:..|||.....:..|:|..|.....:: |..:.|:.||.  |.|.::|
Mouse   452 NCIGQQFAMNEMKVVTALCLLRFEFSPDPSKIPIK-VPQLILRSKNG--IHLYLKP 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	p450	42..503	CDD:299894	116/503 (23%)
Cyp4b1	NP_031849.1	p450	47..500	CDD:278495	123/536 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780