Protein Alignment Cyp318a1 and cyp4b1

DIOPT Version :10

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001120073.1
• Gene: cyp4b1 / 100145080
• XenbaseID: XB-GENE-5924259
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 117/563 - (20%)
• Similarity: 221/563 - (39%)
• Gaps: 105/563 - (18%)

  Fly     4 NIALW----ACGALLAVLLAWQQRKCWRLIWQLNGWRGVIQQ----PVLWLL------------- 47
            |..:|    |...||||||     |..:|.........:.:|    |..|||
 Frog    12 NTLVWQQVAALLCLLAVLL-----KATQLYLSQKRQENIFKQFPGPPRHWLLGNVDQIRRDGKDL 71

  Fly    48 -LCIN-LHPNSILEKVSQYRVHFQRPLAVLVGTRVLLYIDDPAGMECVLNAPECLDKTFLQDGF- 109
             |.:| .|.|.     ..:.|.|.       .....|::..|...:.:....|  .|:.:...|
 Frog    72 DLLVNWTHKNG-----GAFPVWFG-------NFSSFLFLTHPDYAKVIFGREE--PKSSISYDFL 122

  Fly   110 --FVRRGLLHARGQKWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTA 172
              ::.:|||...|.||...|:.|.|.|.::::..:.::.:.....|::.::...........|
 Frog   123 VPWIGKGLLVLTGPKWFQHRRLLTPGFHYDVLKPYVNLISKCTTDMLDNWEKLITKQKTVELF-- 185

  Fly   173 AEDLLSRAVLEVSCLTIMGTPTNFTQLDDAHIAHSYKRLLEISAVRVVK----PWLQIRLLHRLL 233
              ..||...|:..........:|..:  |::.|: .|.:.::|.|..::    |:....:.:  |
 Frog   186 --QHLSLMTLDSIMKCAFSYDSNCQK--DSNNAY-IKAVFDLSYVANLRLRCFPYHNDTVFY--L 243

  Fly   234 APELYEESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRIFIEQIFQLAANG 298
            :|..|...|.| ::..:....:::.:..:.:|      ||..|....  :|.:....|...|.:.
 Frog   244 SPHGYRFRKAC-RITHEHTDKVIQQRKESMKL------EKELEKIQQ--KRHLDFLDILLFARDE 299

  Fly   299 E---MTLEEIMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLEQ 360
            :   ::.:::..|..:.:....:|.::.|...|.|:| ...:.|::...||:.::.|...:..|.
 Frog   300 KGHGLSDDDLRAEVDTFMFEGHDTTASGISWILYCMA-KYPEHQQKCREEIKEVLGDRQIMEWED 363

  Fly   361 LQQLRYLDAFVSESLRLLATVPMNLRHVSRDFR-----LAGRQHETIVPQNSIVVLDTFNMQRDE 420
            |.::.|.:..:.||||:...||    .|:|..|     ..||.    ||..:::.|..:.:.::.
 Frog   364 LGKIPYTNMCIKESLRMYPPVP----GVARQLRNPVTFFDGRS----VPAGTLIGLSIYAIHKNP 420

  Fly   421 RWWGANARQFDPQRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLF 485
            ..| .:...|:|.||..:...                   .|||::||||:.|.|:|||:.:.:.
 Frog   421 AVW-EDPEVFNPLRFSPENSA-------------------NRHSHAFLPFAAGPRNCIGQNFAMN 465

  Fly   486 IMKVFLVKLITNFDFQSDFELEKLQFVENISLKFKNADDILLT 528
            .|||.:...:..|....|.|...:: :..:.||.||...:.||
 Frog   466 EMKVAVALTLNRFHLAPDLENPPIK-IPQLVLKSKNGIHVHLT 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	CYP313-like	69..525	CDD:410680	93/470 (20%)
cyp4b1	NP_001120073.1	CYP4B-like	71..505	CDD:410771	99/495 (20%)