Protein Alignment Cyp318a1 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_727590.1
• Gene: Cyp318a1 / 32172
• FlyBaseID: FBgn0030369
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 544
• Identity: 127/544 - (23%)
• Similarity: 219/544 - (40%)
• Gaps: 103/544 - (18%)

  Fly    11 GALLAVLLAWQ---QRKCWRLIWQLNGWRGVIQQPVLWLLLCINLHPNSILEKVSQYRVHFQRPL 72
            |.||.::.|.|   .||     |.|...:.....|..|............|::|.....||  |.
Mouse    26 GLLLLLVKAVQFYLHRK-----WLLKALQQFPSPPFHWFFGHEQFKGEQELKEVVSCIEHF--PS 83

  Fly    73 AV---LVGTRVLLYIDDPAGMECVL--NAPECLDKTFLQDGFF------VRRGLLHARGQKWKLR 126
            |.   ..|:...|.:.||..|:.:|  :.|:.       :|.:      :..|||...||.|...
Mouse    84 AFPCWFWGSNAYLTVYDPDYMKVILGRSDPKA-------NGIYRLLAPWIGYGLLLLNGQPWFQH 141

  Fly   127 RKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFTAAEDLLSRAVLEVSCLTI-M 190
            |:.|.|||.::|:..:..........|:::::.           .|.:|........:|.:|: .
Mouse   142 RRMLTPAFHYDILKPYVKNMADSIRLMLDKWER-----------LAGQDSSIEIFQHISLMTLDT 195

  Fly   191 GTPTNFTQLDDAHIAHSYKRLLEI---------SAVRVVKPWLQIRLLHRL-----LAPELYEES 241
            .....|:......:..:||..|:.         |.||.:  :.|...::||     ||
Mouse   196 VMKCAFSHKGSVQVDGNYKTYLQAIGDLNNLFHSRVRNI--FHQNDTIYRLSSNGRLA------- 251

  Fly   242 KKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRRI-FIE-QIFQLAANGE-MTLE 303
            |:..:|..|...|::  |.|..:|:|      .||..:...:||: |:: .:|....||: |:.:
Mouse   252 KQACQLAHDHTDGVI--KMRKDQLQD------EGELENIKKKRRLDFLDILLFARMENGDSMSDK 308

  Fly   304 EIMDEAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLLAEIRALVPDVGQVGLEQLQQLRYLD 368
            ::..|..:.:....:|.::.:......|||:. :.|:|...|:::|:.|...:..:.|.|:.|..
Mouse   309 DLRAEVDTFMFEGHDTTASGVSWIFYALATHP-EHQQRCREEVQSLLGDGSSITWDHLDQIPYTT 372

  Fly   369 AFVSESLRLLATVPMNLRHVSRDFRLA-GRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDP 432
            ..:.|:|||...||..:|.:|...... ||.    :|:...|.|..:.:..:.:.| .|...|||
Mouse   373 MCIKEALRLYPPVPGIVRELSTSVTFPDGRS----LPKGVQVTLSIYGLHHNPKVW-PNPEVFDP 432

  Fly   433 QRFLDQEEEQLSKGHNDSGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITN 497
            .||.....                     |||:||||||.|.|:|||:::.:..:||.:...:.:
Mouse   433 SRFAPDSP---------------------RHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLH 476

  Fly   498 FDFQSDFELEKLQFVENISLKFKN 521
            |:...| .....:.:..|.||.||
Mouse   477 FELLPD-PTRVPEPLARIVLKSKN 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp318a1	NP_727590.1	CYP313-like	69..525	CDD:410680	112/483 (23%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	116/494 (23%)