Protein Alignment Cyp311a1 and ERG5

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_013728.1
• Gene: ERG5 / 855029
• SGDID: S000004617
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 529
• Identity: 113/529 - (21%)
• Similarity: 216/529 - (40%)
• Gaps: 113/529 - (21%)

  Fly     1 MALWPLLLITLTIW----ILVRKWTLLRLGSSLPGP----WAFPLLGNAQMVGKLRPEYIFLVFT 57
            :.::..|:..|.:|    ..::|       .|:.||    |  |::|  ..:..|.|:     |.
Yeast    46 LKIFATLICILLVWDQVAYQIKK-------GSIAGPKFKFW--PIIG--PFLESLDPK-----FE 94

  Fly    58 ELRDRFGATYRLRLGP--------QLWVFLHSAEETRQALHDPTLRK---ADTFMQ-LEPLIGNG 110
            |.:.::.:      ||        :..|...:.:..|:.|......|   .|..:: |.|.  |.
Yeast    95 EYKAKWAS------GPLSCVSIFHKFVVIASTRDLARKILQSSKFVKPCVVDVAVKILRPC--NW 151

  Fly   111 LLISHGAHWTRQRRLLTPAFQPQLLRSFAPAI----GGHVERLVGRLGATRG-----AFLEVTEP 166
            :.:...|| |..|:.|...|..|.|..:.|::    ..::::.| ||.....     .|.|:.|.
Yeast   152 VFLDGKAH-TDYRKSLNGLFTKQALAQYLPSLEQIMDKYMDKFV-RLSKENNYEPQVFFHEMREI 214

  Fly   167 LFACLLDAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMIN-PLLSSDWIFQRTQLW---R 227
            |.|..|::.    .|..:....|  ..|...::|.:..|  .::| |:     |...|:.|   :
Yeast   215 LCALSLNSF----CGNYITEDQV--RKIADDYYLVTAAL--ELVNFPI-----IIPYTKTWYGKK 266

  Fly   228 DLDEQLQVIH--SQMESVIEKRAKELLDMGEPAGRAHNLLDTLLLAKFEGQS------------L 278
            ..|..:::..  :||       ||:.:..|   |:...::|.......:.::            .
Yeast   267 TADMAMKIFENCAQM-------AKDHIAAG---GKPVCVMDAWCKLMHDAKNSNDDDSRIYHREF 321

  Fly   279 SRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKE---LQDVALDETTDLDALNGL 340
            :.:||.:.:.||:||..|.:::...::...:|..|:...::|:|   :::..:....:||.:..:
Yeast   322 TNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKM 386

  Fly   341 PYLEALIKEVLRL---YTIVPTTGRQTTQSTEIGGRTYCA--GVTLWINMYGLAHDKEYYPDPYA 400
            .|...:|||.||.   ..:||...::....:.    .|.|  |..|...:|...||.|.|.:|..
Yeast   387 KYTNMVIKETLRYRPPVLMVPYVVKKNFPVSP----NYTAPKGAMLIPTLYPALHDPEVYENPDE 447

  Fly   401 FKPERWLPEDGAVAPPA-FSYIPFSGGPHVCIGRRYSLLLMKLLTAR--LVREFQMELSPEQAPL 462
            |.||||:  :|:.|..| .:::.|..|||||:|:.|.::....|..:  |..:|...::|....:
Yeast   448 FIPERWV--EGSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHHTVTPLSEKI 510

  Fly   463 RLEAQMVLK 471
            ::.|.:..|
Yeast   511 KVFATIFPK 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	99/458 (22%)
ERG5	NP_013728.1	CYP61_CYP710	103..522	CDD:410703	99/450 (22%)