DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp311a1 and DIT2

DIOPT Version :9

Sequence 1:	NP_572780.3	Gene:	Cyp311a1 / 32170	FlyBaseID:	FBgn0030367	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_010690.1	Gene:	DIT2 / 852011	SGDID:	S000002810	Length:	489	Species:	Saccharomyces cerevisiae

Alignment Length:	477	Identity:	113/477 - (23%)
Similarity:	191/477 - (40%)	Gaps:	100/477 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 LVFTELRDRFGATYRLRLGPQLWVFLHSAEETRQALHDPTLRKADTFMQ-----------LEPLI 107
            |...|..:::||. :...|.:..:.:..:|...|...|     .|||.:           |....
Yeast    57 LYIRESMEKYGAV-KFFFGSRWNILVSRSEYLAQIFKD-----EDTFAKSGNQKKIPYSALAAYT 115

  Fly   108 GNGLLISHGAHWTRQRRLLT---------PAFQP-----QLLRSFAPAIGGHVERLVGRLGATRG 158
            |:.::.::||.|...|..:|         |.|:.     .|:::         ..|.|:.....|
Yeast   116 GDNVISAYGAVWRNYRNAVTNGLQHFDDAPIFKNAKILCTLIKN---------RLLEGQTSIPMG 171

  Fly   159 AFLEVTEPLFACL-LDAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMIN------PLLSS 216
                   ||...: ||.|...::|  .|..::.|..  .|||.....:.|::.:      |.|..
Yeast   172 -------PLSQRMALDNISQVALG--FDFGALTHEK--NAFHEHLIRIKKQIFHPFFLTFPFLDV 225

  Fly   217 DWIFQRTQLWRDL--DEQLQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLDTLLLAKFEGQSLS 279
            ..|..|.:.::|:  ..:|.|...|.|.|...:.::.........||||           .:.:.
Yeast   226 LPIPSRKKAFKDVVSFRELLVKRVQDELVNNYKFEQTTFAASDLIRAHN-----------NEIID 279

  Fly   280 RREIRDEINTFVFAGVDTTTAAMSFVLYALAKFP-ETQTRLRKELQDVALDETTDLDALNGLPYL 343
            .:::.|.|...:.||.:......:..||.|||:. |.|.:||||:..:     ||...|..||.|
Yeast   280 YKQLTDNIVIILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGI-----TDPKGLADLPLL 339

  Fly   344 EALIKEVLRLYTIVPT-TGRQTTQSTEIGGRTYC-AGVTLWINMYGLAHD-KEYYPDPYAFKPER 405
            .|.:.||:|:|..:.| ..|.||::.::|..... .||.:..|.:|.:|| |.:......|||||
Yeast   340 NAFLFEVVRMYPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPER 404

  Fly   406 W------LPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPE------ 458
            |      :.::..:|....:...|.||...|:|.:.:|..|::..|.::::|:..|.||
Yeast   405 WGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLT 469

  Fly   459 ----QAPLRLEAQMVLKAQQGI 476
                ..||.|:    ||..:.|
Yeast   470 PAGPLCPLNLK----LKFNENI 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	113/477 (24%)
DIT2	NP_010690.1	CYP56-like	65..485	CDD:410693	110/465 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	1.000	Domainoid score	I1949
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000