DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp311a1 and CYP721A1

DIOPT Version :9

Sequence 1:	NP_572780.3	Gene:	Cyp311a1 / 32170	FlyBaseID:	FBgn0030367	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_177649.1	Gene:	CYP721A1 / 843850	AraportID:	AT1G75130	Length:	505	Species:	Arabidopsis thaliana

Alignment Length:	544	Identity:	136/544 - (25%)
Similarity:	225/544 - (41%)	Gaps:	104/544 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALWPLLLITLTIWILVRK------WTLLRLGS-----SLPGPWAFPLLGNAQMVGKL------R 48
            ||::  .::.|..:.||.:      |...|:.|     |:.||......||:..|.:|      :
plant     1 MAVF--FILVLVFFFLVFRFIYSNIWVPWRIQSHFKKQSVTGPSYRIFSGNSGEVSRLTAEAKSK 63

  Fly    49 P--------EYIFLV---FTELRDRFGATYRLRLGPQLWVFLHSAEETRQAL----------HDP 92
            |        |::..|   :.|....:|.|:....|.:..|........|:||          |:|
plant    64 PIPSGRNPHEFVHRVAPHYHEWSRVYGKTFLYWFGSKPVVATSDPRLIREALTTGGSFDRIGHNP 128

  Fly    93 TLRKADTFMQLEPLIGNGLLISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGATR 157
             |.|.        |...||....|..|...||:...||..:.|:.:.|.:......|:.:....|
plant   129 -LSKL--------LYAQGLPGLRGDQWAFHRRIAKQAFTMEKLKRWVPQMVTSTMMLMEKWEDMR 184

  Fly   158 GA----FLEVTEPLFACLLDAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDW 218
            ..    .|||.:.:.....:.:..|:.|     .||:....|  |.|..:::  |:...:..|.:
plant   185 NGGEEIELEVHKEMHNLSAEMLSRTAFG-----NSVEEGKGI--FELQERMM--RLFYLVRWSVY 240

  Fly   219 I--FQ------RTQLWRDLDEQLQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLDTLLLAKFEG 275
            |  |:      ..::|| :::|::|      |::     :|::..:.|......|....::.:..
plant   241 IPGFRFFPSKTNREIWR-IEKQIRV------SIL-----KLIENNKTAVEKSGTLLQAFMSPYTN 293

  Fly   276 QS-----LSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDET--TD 333
            |:     |...|:.||..||.||..:||...|:|||..||...|.|...|:|:..| |.:|  ..
plant   294 QNGQEEKLGIEEVTDECKTFYFAAKETTANLMTFVLVLLAMNQEWQNIAREEVICV-LGQTGLPT 357

  Fly   334 LDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYY-PD 397
            ||.|..|..|..:|.|.||||....|..|.|.:..::|.....||..|::::..:.||||.: .|
plant   358 LDILQDLKTLSMIINETLRLYPPAMTLNRDTLKRAKLGDLDIPAGTQLYLSVVAMHHDKETWGDD 422

  Fly   398 PYAFKPERWLPEDGAVAPPAFS--YIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPE-- 458
            ...|.|.|:  ||    |...|  .:||..||..|:|:..::...|.:.|.:::.:...|||.
plant   423 AEEFNPRRF--ED----PKKQSALLVPFGLGPRTCVGQNLAVNEAKTVLATILKYYSFRLSPSYA 481

  Fly   459 QAPLRLEAQMVLKAQQGINVSFLK 482
            .||:..   :.|:.|.|.::.|.:
plant   482 HAPVLF---VTLQPQNGAHLLFTR 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	126/500 (25%)
CYP721A1	NP_177649.1	p450	26..495	CDD:386267	128/508 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	4.010