DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp311a1 and CYP714A2

DIOPT Version :9

Sequence 1:	NP_572780.3	Gene:	Cyp311a1 / 32170	FlyBaseID:	FBgn0030367	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_197872.1	Gene:	CYP714A2 / 832559	AraportID:	AT5G24900	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	545	Identity:	130/545 - (23%)
Similarity:	226/545 - (41%)	Gaps:	105/545 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ALWPLLLITL-----TIW--ILVRKWTLLR----LGSSLPGPWAFPLLGNAQMVGKLRPE----- 50
            |:|.::::.:     .::  .:|.:|.:.|    .|...|.|..|.  ||...:.:::.|
plant    11 AIWCIVIVGIFSVGYHVYGRAVVEQWRMRRSLKLQGVKGPPPSIFN--GNVSEMQRIQSEAKHCS 73

  Fly    51 -----------YIFLVFTELRDRFGATYRLRLGPQLWVFLHSAEETRQALHDPTL---RKADTFM 101
                       .:|..|...|.::|..|....|.:..::::..|..::.....||   |......
plant    74 GDNIISHDYSSSLFPHFDHWRKQYGRIYTYSTGLKQHLYINHPEMVKELSQTNTLNLGRITHITK 138

  Fly   102 QLEPLIGNGLLISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRL---------GATR 157
            :|.|::|||::.|:|.||..|||::...|....::..   :|..||..:..|         |...
plant   139 RLNPILGNGIITSNGPHWAHQRRIIAYEFTHDKIKGM---VGLMVESAMPMLNKWEEMVKRGGEM 200

  Fly   158 GAFLEVTEPLFACLLDAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQR 222
            |..:.|.|.|.....|.|.....|:...               ..|.:|. ||..||::  |.:|
plant   201 GCDIRVDEDLKDVSADVIAKACFGSSFS---------------KGKAIFS-MIRDLLTA--ITKR 247

  Fly   223 TQLWR-----DL--------DEQLQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLDT----LLL 270
            :.|:|     |:        |..:..:..::||.|.:..||         |.....||    |:.
plant   248 SVLFRFNGFTDMVFGSKKHGDVDIDALEMELESSIWETVKE---------REIECKDTHKKDLMQ 303

  Fly   271 AKFEG-----------QSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQ 324
            ...||           :|..||.:.|...:..|||.|:|..::|:.|..||..|..|.::|.|:.
plant   304 LILEGAMRSCDGNLWDKSAYRRFVVDNCKSIYFAGHDSTAVSVSWCLMLLALNPSWQVKIRDEIL 368

  Fly   325 DVALDETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLA 389
            ....:...|.:::..|..:..:|:|.:|||...|..||:.::...:|......||.:|..:..|.
plant   369 SSCKNGIPDAESIPNLKTVTMVIQETMRLYPPAPIVGREASKDIRLGDLVVPKGVCIWTLIPALH 433

  Fly   390 HDKEYY-PDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQM 453
            .|.|.: ||...|||||:............|||||..||..|:|:.:.::.:|:|.:.:|.:|..
plant   434 RDPEIWGPDANDFKPERFSEGISKACKYPQSYIPFGLGPRTCVGKNFGMMEVKVLVSLIVSKFSF 498

  Fly   454 ELSP--EQAPLRLEAQMVLKAQQGI 476
            .|||  :.:|   ..:::::.|.|:
plant   499 TLSPTYQHSP---SHKLLVEPQHGV 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	124/506 (25%)
CYP714A2	NP_197872.1	p450	37..524	CDD:299894	126/519 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D786853at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.930