DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp311a1 and CYP76C1

DIOPT Version :9

Sequence 1:	NP_572780.3	Gene:	Cyp311a1 / 32170	FlyBaseID:	FBgn0030367	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_850439.1	Gene:	CYP76C1 / 819164	AraportID:	AT2G45560	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	505	Identity:	124/505 - (24%)
Similarity:	204/505 - (40%)	Gaps:	89/505 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALWPLLLITLTIWILVRKWTLLRLGSSL-PGPWAFPLLGNAQMVGKLRPEYIFLVFTELRDRFG 64
            :.|:..:|....|:...|...:.|..::| |||...|::||..:|||    :....|.||...:|
plant    10 LLLFCFILSCFLIFTTTRSGRISRGATALPPGPPRLPIIGNIHLVGK----HPHRSFAELSKTYG 70

  Fly    65 ATYRLRLGPQLWVFLHSAEETRQAL--HD-------PTLRKADTFMQLEPLIGNGLLISHGAHWT 120
            ....|:||....|.:.|.|..|:.|  ||       ||........|...|:   .|.|..|.|.
plant    71 PVMSLKLGSLNTVVIASPEAAREVLRTHDQILSARSPTNAVRSINHQDASLV---WLPSSSARWR 132

  Fly   121 RQRRL-LTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEPLFACLLDAIVDTSMGAQL 184
            ..||| :|....||                  |:.||:...:...:.|.     :.:..|...:
plant   133 LLRRLSVTQLLSPQ------------------RIEATKALRMNKVKELV-----SFISESSDRE- 173

  Fly   185 DTQSVDHSPI--IQAFHLSSKLLF---------KRMIN---------------PLLSSDWIFQRT 223
              :|||.|.:  |...::.|.:||         |..||               |..::.:.|.|
plant   174 --ESVDISRVAFITTLNIISNILFSVDLGSYNAKASINGVQDTVISVMDAAGTPDAANYFPFLR- 235

  Fly   224 QLWRDLDEQLQVIHSQMESV-------IEKRAKELLDMGEPAGRAHN-LLDTLLLAKFEGQSLSR 280
              :.||...::......|.:       |:.:..|......|...:.| .:|.||..|.:...||.
plant   236 --FLDLQGNVKTFKVCTERLVRVFRGFIDAKIAEKSSQNNPKDVSKNDFVDNLLDYKGDESELSI 298

  Fly   281 REIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDV----ALDETTDLDALNGLP 341
            .:|...:.....||.||:::.:.:.:..|.|.|:|..:.:.|:..|    .:.|.:|   ::.||
plant   299 SDIEHLLLDMFTAGTDTSSSTLEWAMTELLKNPKTMAKAQAEIDCVIGQNGIVEESD---ISKLP 360

  Fly   342 YLEALIKEVLRLYTIVP-TTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPER 405
            ||:|::||..||:|.|| ...|:.....||.|........:.:|::.:..|...:.:|..|:|||
plant   361 YLQAVVKETFRLHTPVPLLIPRKAESDAEILGFMVLKDTQVLVNVWAIGRDPSVWDNPSQFEPER 425

  Fly   406 WLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMEL 455
            :|.:|..|....:...||..|..:|.|...::..:.|:.|.|:..|..:|
plant   426 FLGKDMDVRGRDYELTPFGAGRRICPGMPLAMKTVSLMLASLLYSFDWKL 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	118/475 (25%)
CYP76C1	NP_850439.1	p450	11..505	CDD:386267	124/504 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910