Protein Alignment Cyp311a1 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 496
• Identity: 138/496 - (27%)
• Similarity: 244/496 - (49%)
• Gaps: 36/496 - (7%)

  Fly     7 LLITLTIWILVRKWTLLRLGSSLPGPWAFPLLGNAQMVGKLRPEYIFLVFTELRDRFGATYRLRL 71
            |::...:.:.:|:..|||..|..|||.|..|||:.:.:.:...|    ...|:..:....:...:
Mouse    24 LVLMQAMKLYLRRQRLLRDLSPFPGPPAHWLLGHQKFLQEDNME----TLDEIVKKHPCAFPCWV 84

  Fly    72 GPQLWVFLHSAEETRQALHDPT-----LRKADTFMQ-----LEPLIGNGLLISHGAHWTRQRRLL 126
            || ...|.:        ::||.     |.:.|..||     |.|.||.|||...|..|.:.|.||
Mouse    85 GP-FQAFFY--------IYDPDYAKIFLSRTDPKMQYLHQLLTPCIGRGLLNLDGPRWFQHRCLL 140

  Fly   127 TPAFQPQLLRSFAPAIGGHVERLVG---RLGATRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQ- 187
            ||||...:|:.....:...|:.::.   ::..|:...:||.|.:....||.|:..:.|.:.:.|
Mouse   141 TPAFHQDILKPCVDTMAHSVKVMLDKWEKMWTTQETTIEVFEHINLMTLDIIMKCAFGQETNCQI 205

  Fly   188 SVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEKRAKELL 252
            :..:...::|.....:::..|:.|.....|.||:.:.......|..:|||...|.:|:.|.|.|.
Mouse   206 NGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLSPKGHCFQELGKVIHQYTEKIIQDRKKILK 270

  Fly   253 DM--GEPAGRAHNLLDTLLLAKFEGQ-SLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPE 314
            :.  .:....:...||.:|.|:.|.: :.|..::|.|:|||::||.|.:.|::|::||.||..||
Mouse   271 NQVKQDDTQTSQIFLDIVLSAQAEDERAFSDADLRAEVNTFMWAGHDASAASISWLLYCLALNPE 335

  Fly   315 TQTRLRKELQDVALD-ETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEI-GGRTYCA 377
            .|.|.|.|::.:..| .:...:.|:.:.|....|||.|||...||:..|:.::...: .|.:..|
Mouse   336 HQDRCRTEIRSILGDGSSITWEQLDEMSYTTMCIKETLRLIPPVPSISRELSKPLTLPDGHSLPA 400

  Fly   378 GVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKL 442
            |:|:.::::||.|:...:.||..|.|.|:..|:.....|. :::|||.||..|||:::::|.:|:
Mouse   401 GMTVVLSIWGLHHNPAVWNDPKVFDPLRFTKENSDQRHPC-AFLPFSSGPRNCIGQQFAMLELKV 464

  Fly   443 LTARLVREFQMELSPE-QAPLRLEAQMVLKAQQGINVSFLK 482
            ..|.::..||  ::|: ..|....:..||:.:.||.:...|
Mouse   465 AIALILLHFQ--VAPDLTRPPAFSSHTVLRPKHGIYLHLKK 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	122/433 (28%)
Cyp4x1	NP_001003947.1	CYP4B-like	66..500	CDD:410771	124/449 (28%)