Protein Alignment Cyp311a1 and Cyp4f37

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001093657.1
• Gene: Cyp4f37 / 677156
• MGIID: 3780112
• Length: 546
• Species: Mus musculus
• Alignment Length: 528
• Identity: 155/528 - (29%)
• Similarity: 240/528 - (45%)
• Gaps: 89/528 - (16%)

  Fly     4 WPLLLITLTIWILVR--KWTL--------LRLGSSLPGP----WAFPLLGNAQMVGKLRPEYIFL 54
            |.|||:....|||.|  .||.        ||   ..|.|    |   .||:..|:.  ..|....
Mouse    19 WHLLLLGAASWILARILAWTYSFCENCSRLR---CFPQPPKRNW---FLGHLGMIE--HNEEGMQ 75

  Fly    55 VFTELRDRFGATYR----LRLGPQLWVFLHSAEETRQALHDPTLRKAD----------------- 98
            :.||.    |.|||    ..|||.:                |.||..|
Mouse    76 LMTEA----GQTYRDVHLCWLGPVI----------------PVLRIVDPAFVAPLLLASALVAPK 120

  Fly    99 -----TFMQLEPLIGNGLLISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGR---LGA 155
                 ||  ::|.:|:||.::.|..|:|.||||||||...:|:.:.......|..:..:   |.:
Mouse   121 DTTFHTF--VKPWLGDGLFLNSGDKWSRHRRLLTPAFHFDILKPYVKIFNQSVNIMHAKWKHLSS 183

  Fly   156 TRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIF 220
            ...|.||:.|.:....||::.....|...:.|......|.....||| |:.||.....|..|:::
Mouse   184 EGSARLEMFEHISLMTLDSLQKCLFGFDSNCQESPSEYISAILELSS-LVIKRSHQLFLFVDFLY 247

  Fly   221 QRTQLWRDLDEQLQVIHSQMESVIEKRAKELLDM-------GEPAGRAHNLLDTLLLAKFE-GQS 277
            ..|...|...:...::|:..::||.:|...|...       .:...:..:.:|.|||||.| |:.
Mouse   248 YHTADGRRFRKACDLVHNFTDAVIRERRHTLSSQNHDEFLKSKTKSKTLDFIDVLLLAKDEHGKE 312

  Fly   278 LSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVAL---DETTDLDALNG 339
            ||..:||.|.:||:|.|.|||.:|:|::||.||:.||.|.|.|:|:|::..   .:..:.|.|..
Mouse   313 LSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQELLRGREPQEIEWDDLAQ 377

  Fly   340 LPYLEALIKEVLRLYTIVPTTGRQTTQSTEI-GGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKP 403
            ||:|...|||.|||:..|....|:.|:...: .||....|....|:::|:.|:...:|||..:.|
Mouse   378 LPFLTMCIKESLRLHPPVIDLLRRCTRDIVLPDGRVIPKGNICVISIFGIHHNPSVWPDPEVYDP 442

  Fly   404 ERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQM 468
            .|:.||:....|| .::||||.||..|||:.:::..|.:..|..:..|:  :.|:....|.:.::
Mouse   443 FRFDPENAHKRPP-LAFIPFSAGPRNCIGQTFAMNEMMVALALTLLRFR--ILPDDKEPRRKPEI 504

  Fly   469 VLKAQQGI 476
            :|:|:.|:
Mouse   505 ILRAEGGL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	134/454 (30%)
Cyp4f37	NP_001093657.1	CYP4F	74..515	CDD:410772	136/465 (29%)