Protein Alignment Cyp311a1 and Cyp4a31

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_964002.2
• Gene: Cyp4a31 / 666168
• MGIID: 3028580
• Length: 509
• Species: Mus musculus
• Alignment Length: 499
• Identity: 150/499 - (30%)
• Similarity: 253/499 - (50%)
• Gaps: 42/499 - (8%)

  Fly     6 LLLITLTIWILVRKWTLLRLGSSLPGP---WAFPLLGNAQMVGKLRPEYIFLVFTELRDRFGATY 67
            |||:......|.||| ||:.....|.|   |.|   |:.|..|....:.|..........|.
Mouse    29 LLLVKAVQVYLHRKW-LLKALQQFPSPPFHWFF---GHEQFKGDQELQEIVSCIENFPSAFP--- 86

  Fly    68 RLRLGPQLWVFLHSAEETRQAL--HDPTLRKADTFMQLEPLIGNGLLISHGAHWTRQRRLLTPAF 130
            |...|.:.::.::..:..:..|  .||....|  :..|.|.||.|||:.:|..|.:.|::|||||
Mouse    87 RWFWGSKAYLTVYDPDYMKVILGRSDPKANGA--YRLLAPWIGYGLLLLNGQSWFQHRKMLTPAF 149

  Fly   131 QPQLLRSFAPAIGGHV-------ERLVGRLGATRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQS 188
            ...:|:::...:...:       |||.|     :.:.:|:.:.:....||.::..:...:...|
Mouse   150 HYDILKTYVKNMADSIRLMLDKWERLAG-----QDSSIEIFQHISLMTLDTVMKCAFSHKGSVQ- 208

  Fly   189 VD--HSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEKRAKEL 251
            ||  :...:||....:.|:..|:.|....:|.|::.:...|..::..|:.|...:.||:.|..:|
Mouse   209 VDGNYKTYLQAIGDLNNLVHSRVRNMFHQNDTIYKLSSNGRLSNQACQLAHDHTDGVIKMRKDQL 273

  Fly   252 LDMGE----PAGRAHNLLDTLLLAKFEGQ-SLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAK 311
            .|.||    ...|..:.||.||.|:.|.: |:|.:::|.|::||:..|.|||.:.:|::.||||.
Mouse   274 QDEGELENIKKKRRLDFLDILLFARMENEDSMSDKDLRAEVDTFMIEGHDTTASGVSWIFYALAT 338

  Fly   312 FPETQTRLRKELQDVALD-ETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQ-TTQSTEIGGRT 374
            .||.|.|.|:|:|.:..| .:...|.|:.:||....|||.||||..||:.||: :|..|...|.:
Mouse   339 HPEHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPSIGRELSTSVTFPDGCS 403

  Fly   375 YCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAP-PAFSYIPFSGGPHVCIGRRYSLL 438
            ...||.:.:::|||.|:.:.:|:|..|.|.|:.|:    :| .:.|::|||||...|||:::::.
Mouse   404 LPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPD----SPRHSHSFLPFSGGARNCIGKQFAMS 464

  Fly   439 LMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINVSFLK 482
            .:|::.|..:..|::...|.:.|:.| |:.|||::.||.:...|
Mouse   465 ELKVIVALTLLRFELLPDPTRVPMSL-ARFVLKSKNGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	131/432 (30%)
Cyp4a31	NP_964002.2	CYP4B-like	71..504	CDD:410771	133/448 (30%)