Protein Alignment Cyp311a1 and Cyp3a57

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 518
• Identity: 141/518 - (27%)
• Similarity: 236/518 - (45%)
• Gaps: 71/518 - (13%)

  Fly     4 WPLLLITLTIWILVRKWT---LLRLGSSLPGPWAFPLLGNAQMVGKLRPEYIFLVFTELRDRFGA 65
            |.||:.:|..:.:...::   ..:||  :|||...||.||  ::..|...:.|  ..:...::|.
Mouse    12 WVLLVTSLVFFYIYGTYSHGLFKKLG--IPGPKPLPLFGN--IINYLDGMWKF--DDDCYKKYGK 70

  Fly    66 TYRLRLGPQLWVFLHSAEETRQALHDPTLRKA-------DTFMQLEP-----LIGNGLLISHGAH 118
            .:....|||..:          |:.||.:.|.       ..|....|     .:...:.||....
Mouse    71 IWGFYEGPQPIL----------AIMDPEIIKIVLVKECYSVFTNRRPFGPVGFLKKSITISEDEE 125

  Fly   119 WTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEPL------FACLLDAIVD 177
            |.|.|.||:|.|....|:...|.:..:.:.||..|....    |..||:      .|..:|.|..
Mouse   126 WKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREE----EKEEPINMKDIFGAYSMDVITG 186

  Fly   178 TSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQ-RTQLWRDLDEQLQVIHSQ-- 239
            ||.|..:|:.:....|.:|..   .|:|..:..:|.|.|..:|. .|.::..|:  |.:...|
Mouse   187 TSCGVNIDSLNNPQDPFVQKI---KKILKFKFFDPFLLSVVLFPFLTPIYEMLN--LSIFPRQSM 246

  Fly   240 --MESVIEKRAKELLDMGEPAGRAHNLLDTLLL----AKFEGQ----SLSRREIRDEINTFVFAG 294
              .:..::|..|:.||..:     .|.:|.|.|    ...:||    :||..|:..:...|:|.|
Mouse   247 NFFKKFVKKMKKDRLDYNQ-----KNRVDFLQLMMNTQNSKGQESLKALSDLEMAAQTLIFIFGG 306

  Fly   295 VDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDL--DALNGLPYLEALIKEVLRLYTIV 357
            .|.|:.::||::|.||..|:.|.:|:.|: |.||.....:  |||..:.||:.::.|.||||.:|
Mouse   307 YDGTSTSISFIMYELATHPDVQKKLQDEI-DRALPNKAPVTYDALMDMEYLDMVVNESLRLYPVV 370

  Fly   358 PTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPED-GAVAPPAFSYI 421
            ....|.:.:..||.|.....|..:.|.:|.|..|.||:|:|..|.|||:..|: |.:.|  :.|:
Mouse   371 SRIDRFSKKDVEIHGVFIPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFSKENKGNIDP--YIYM 433

  Fly   422 PFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPE-QAPLRLEAQMVLKAQQGINVSFLKQ 483
            ||..||..|||.|::|:.:||....:::.|.::...| |.|:::..|.:.:.::.|.:.|:.:
Mouse   434 PFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEETQIPVKISRQPIFRPEKPIILKFVSR 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	125/448 (28%)
Cyp3a57	NP_001093650.1	cytochrome_P450	67..492	CDD:477761	125/451 (28%)