Protein Alignment Cyp311a1 and cyp46a1.3

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 490
• Identity: 132/490 - (26%)
• Similarity: 225/490 - (45%)
• Gaps: 47/490 - (9%)

  Fly     1 MALWPLL-LITLTIWILVRKWTLLRLG---------SSLPGPWAFP----LLGNAQMVGKLRPEY 51
            |.||.|: ...|.:..|:....||..|         ..:|||   |    .||::..:.:|....
 Frog     1 MGLWALIGWAALLLLALILICFLLFSGYIHYIHMKYDHIPGP---PRDSFFLGHSPTMLRLMKNN 62

  Fly    52 IFLV--FTELRDRFGATYRLRLGPQLWVFLHSAEETRQALHDPTLRKADTFMQL------EPLIG 108
            :.:.  |.....::|...|:....::.:.:.|.|..::.|..|...| |.|..:      ...:|
 Frog    63 LLMYDHFLGWVQKYGPVVRINGLHRVIILVVSPEAVKELLMSPKYSK-DKFYDVIANMFGVRFMG 126

  Fly   109 NGLLISHG-AHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRL--GATRGAFLEVTEPLFAC 170
            .||:.... .||.:|||::.|||....|...........|.|:.:|  .|.....:::.:.|...
 Frog   127 KGLVTDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLMEKADGKCEIKMHDMLSRL 191

  Fly   171 LLDAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQV 235
            .||.|...:.|.:|::.:.|.:|..:|..|..|.:.: |.||::.  :...:....|.:.|.:::
 Frog   192 TLDVIGKVAFGMELNSLNDDLTPFPKAISLVMKGIVE-MRNPMVR--YSLAKRGFIRKVQESIRL 253

  Fly   236 IHSQMESVIEKRAKELLDMGE--PAGRAHNLLDTLLLAKFEGQSLSRREIRDEINTFVFAGVDTT 298
            :....:..||:|.|::.| ||  |.    ::|..:|......:......:.|...||..||.:||
 Frog   254 LRQTGKECIERRQKQIQD-GEEIPV----DILTQILKGAAMEEECDPEILLDNFVTFFIAGQETT 313

  Fly   299 TAAMSFVLYALAKFPETQTRLRKELQDVALDETTDL--DALNGLPYLEALIKEVLRLYTIVPTTG 361
            ...:|||:..|.:.||...:.:.|:.:| :....|:  :.|..|.||..::||.||||...|.|.
 Frog   314 ANQLSFVVMELGRNPEILEKAQAEIDEV-IGSKRDIEYEDLGKLQYLSQVLKETLRLYPTAPGTS 377

  Fly   362 RQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAP-PAFSYIPFSG 425
            |..|:...|.|......||:.:|.|.:...::||.||..|.|:|:.|:    || |.:||.|||.
 Frog   378 RGLTEDMVIDGVKVPENVTIMLNSYIMGRMEQYYSDPLTFNPDRFSPD----APKPYYSYFPFSL 438

  Fly   426 GPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQA 460
            ||..|||:.:|.:..|::.|:|::.::.||:..|:
 Frog   439 GPRSCIGQVFSQMEAKVVMAKLLQRYEFELAEGQS 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	115/411 (28%)
cyp46a1.3	NP_001027517.1	CYP46A1-like	66..490	CDD:410706	116/422 (27%)