Protein Alignment Cyp311a1 and CYP26B1

DIOPT Version :9

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_063938.1
• Gene: CYP26B1 / 56603
• HGNCID: 20581
• Length: 512
• Species: Homo sapiens
• Alignment Length: 525
• Identity: 134/525 - (25%)
• Similarity: 209/525 - (39%)
• Gaps: 109/525 - (20%)

  Fly     6 LLLITLTIWILVRKWTLLRLGS-SLP---GPWAFPLLGNA-----QMVGKLRPEYIFLVFTELRD 61
            ||.::..:|.|  :|...|..| .||   |...|||:|..     |..|         ..:..|:
Human    25 LLAVSQQLWQL--RWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSG---------FQSSRRE 78

  Fly    62 RFGATYRLRLGPQLWVFLHSAEETRQAL---HD--PTLRKADTFMQLEPLIGNGLLISHGAHWTR 121
            ::|..::..|..:..:.:..||..|:.|   |.  .|.....|.|.|.|   |.:..|.|.....
Human    79 KYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGP---NTVSNSIGDIHRN 140

  Fly   122 QRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEPLFACLLDAIVDTSMGAQLDT 186
            :|::.:..|..:.|.|:.|.|     :||                        |.||     |..
Human   141 KRKVFSKIFSHEALESYLPKI-----QLV------------------------IQDT-----LRA 171

  Fly   187 QSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEK----- 246
            .| .|...|..:..:.||.|:..|..||.    |...:  .||....:|....:::|...
Human   172 WS-SHPEAINVYQEAQKLTFRMAIRVLLG----FSIPE--EDLGHLFEVYQQFVDNVFSLPVDLP 229

  Fly   247 --------RAKELLDMG-EPAGR-------AHNLLDTLLL----AKFEGQSLSRREIRDEINTFV 291
                    :|:::|..| |.|.|       ..:.||.|.|    :|..|:.::.:|::|.....:
Human   230 FSGYRRGIQARQILQKGLEKAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELI 294

  Fly   292 FAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVAL--------DETTDLDALNGLPYLEALIK 348
            ||...||.:|.:.::..|.|.|....:||.||:...:        :.|..||.|:||.||:.:||
Human   295 FAAYATTASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIK 359

  Fly   349 EVLRLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGL--AHD-KEYYPDPYAFKPERWLPED 410
            ||:||:|.:....|...|:.|:.|.....|   |..||.:  .|| ...:.|...|.|:|:....
Human   360 EVMRLFTPISGGYRTVLQTFELDGFQIPKG---WSVMYSIRDTHDTAPVFKDVNVFDPDRFSQAR 421

  Fly   411 GAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQG 475
            .......|.|:||.||...|:|:..:.|.:|:|...|....:.||:....| |:....||....|
Human   422 SEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFP-RITLVPVLHPVDG 485

  Fly   476 INVSF 480
            ::|.|
Human   486 LSVKF 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	125/498 (25%)
CYP26B1	NP_063938.1	p450	23..490	CDD:325183	133/523 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4824
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950