Protein Alignment Cyp311a1 and Cyp4f1

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_062569.2
• Gene: Cyp4f1 / 56266
• RGDID: 70926
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 155/511 - (30%)
• Similarity: 248/511 - (48%)
• Gaps: 55/511 - (10%)

  Fly     4 WPLLLITLTIWILV----------RKWTLLRLGSSLPGP----WAFPLLGNAQMVGKLRP-EYIF 53
            |..||:....|||.          |.:..||   ..|.|    |   |:|:   ||.:.| |...
  Rat    19 WQTLLLFGASWILAQILTQIYAAYRNFRRLR---GFPQPPKRNW---LMGH---VGMVTPTEQGL 74

  Fly    54 LVFTELRDRFGATYRLRLGPQLWVF-LHSAEETRQALHDP---TLRKADTFMQLEPLIGNGLLIS 114
            ...|.|...:...:.:.:||.:.|. |..::..|..|:..   .|:....:..|:|.:|:|||:|
  Rat    75 KELTRLVGTYPQGFLMWIGPMVPVITLCHSDIVRSILNASAAVALKDVIFYTILKPWLGDGLLVS 139

  Fly   115 HGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHV-------ERLVGRLGATRGAFLEVTEPLFACLL 172
            .|..|:|.||:|||||...:|:.:........       :||:.. |::|   |::.|.:....|
  Rat   140 AGDKWSRHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWKRLISE-GSSR---LDMFEHVSLMTL 200

  Fly   173 DAIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIH 237
            |::.........:.|......|.....||: |:.||...|||..|.::..|.......:...::|
  Rat   201 DSLQKCVFSFDSNCQEKSSEYIAAILELSA-LVAKRHQQPLLFMDLLYNLTPDGMRFHKACNLVH 264

  Fly   238 SQMESVIEKRAKELLDMG-------EPAGRAHNLLDTLLLAKFE-GQSLSRREIRDEINTFVFAG 294
            ...::||.:|.:.|.|.|       :...:..:.:|.|||.|.| |:.||..:||.|.:||:|.|
  Rat   265 EFTDAVIRERRRTLPDQGLDEFLKSKAKSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMFEG 329

  Fly   295 VDTTTAAMSFVLYALAKFPETQTRLRKELQDVALD---ETTDLDALNGLPYLEALIKEVLRLYTI 356
            .|||.:.:|::||.|||.||.|.|.|:|:|::..|   |..:.|.|..||:|...|||.|||:..
  Rat   330 HDTTASGLSWILYNLAKHPEYQERCRQEVQELLRDRDPEEIEWDDLAQLPFLTMCIKESLRLHPP 394

  Fly   357 VPTTGRQTTQSTEI-GGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSY 420
            |....|..||...: .|||...|:...|:::|:.|:...:|||..:.|.|:.||:...:.| .::
  Rat   395 VTVISRCCTQDILLPDGRTIPKGIICLISIFGIHHNPSVWPDPEVYNPFRFDPENIKDSSP-LAF 458

  Fly   421 IPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGI 476
            ||||.||..|||:.:::..||:..|..:..|:  |.|:....|.:.:::|:|:.|:
  Rat   459 IPFSAGPRNCIGQTFAMSEMKVALALTLLRFR--LLPDDKEPRRQPELILRAEGGL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	135/436 (31%)
Cyp4f1	NP_062569.2	CYP4F	74..515	CDD:410772	137/447 (31%)