DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp311a1 and cyp4v7

DIOPT Version :9

Sequence 1:	NP_572780.3	Gene:	Cyp311a1 / 32170	FlyBaseID:	FBgn0030367	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_001073465.1	Gene:	cyp4v7 / 562008	ZFINID:	ZDB-GENE-061103-88	Length:	510	Species:	Danio rerio

Alignment Length:	498	Identity:	155/498 - (31%)
Similarity:	262/498 - (52%)	Gaps:	42/498 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLLITLTIW----ILVRKWTLLRLGSSLPG-PWAFPLLGNAQMVGKLRPEYIFLVFTEL-----R 60
            |||:..|.:    ..:.||..:|   .:|| ..|:|::|||........::    |.::     .
Zfish    19 LLLLASTAYNPLKNYIGKWNEMR---PIPGMAGAYPIIGNALQFKTNAGDF----FNQIIEGTNE 76

  Fly    61 DRFGATYRLRLGPQLWVFLHSAEETRQALHDPT-LRKADTFMQLEPLIGNGLLISHGAHWTRQRR 124
            :|.....::.:||..::.|:.||.....|.:.. |.|:.::..|.|.:|.|||.|.|..|..:|:
Zfish    77 NRHLPLAKVWVGPVPFLILYHAENIEVVLSNSRHLDKSYSYRFLHPWLGTGLLTSTGEKWRNRRK 141

  Fly   125 LLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEP------LFACLLDAIVDTSMGAQ 183
            :|||.|...:|..|...:....:.|:.::..     ||..||      :..|.||.|.:|:||.:
Zfish   142 MLTPTFHFSILSDFLEVMNEQTDILIQKMQK-----LEDGEPFNCFNFITLCALDIICETAMGKK 201

  Fly   184 LDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEKRA 248
            :..||...|..:|:.:..|.::.||...|.|..|||:.:.:..::..::|:::||...:||.:||
Zfish   202 IYAQSNADSEYVQSVYKMSDIITKRQRAPWLWPDWIYNKLKEGKEHAKRLKILHSFTANVIRERA 266

  Fly   249 KEL-------LDMGEPAGRAHNLLDTLLLAKFE-GQSLSRREIRDEINTFVFAGVDTTTAAMSFV 305
            :.:       .|.||...:|  .||.||...:| ||.||..:|::|::||:|.|.|||.|:|::.
Zfish   267 EFMSSEPDSDSDQGERKRQA--FLDMLLKTTYENGQKLSHEDIQEEVDTFMFEGHDTTAASMNWA 329

  Fly   306 LYALAKFPETQTRLRKELQDV--ALDETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQST 368
            |:.:...||.|..::.|||:|  :.:....::.|..|.|||.:|||.||::..||...|...::.
Zfish   330 LHLIGSHPEVQKAVQAELQEVFGSSERHVGVEDLKKLRYLECVIKESLRIFPSVPLFARSICEAC 394

  Fly   369 EIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGR 433
            .|.|.....||...|..|.|..|..|:|:|..|:|||::||:.....| ::|||||.||..|||:
Zfish   395 HINGFKVPKGVNAVIIPYALHRDPRYFPEPEEFQPERFMPENSKGRHP-YAYIPFSAGPRNCIGQ 458

  Fly   434 RYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGI 476
            |::::..|::.|.::|.|.:|....:..||...:::|:.::||
Zfish   459 RFAMMEEKVVLATILRHFDVEACQSREELRPLGELILRPEKGI 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	148/470 (31%)
cyp4v7	NP_001073465.1	p450	44..505	CDD:278495	148/470 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010