Protein Alignment Cyp311a1 and cyp4b1.2

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001017348.1
• Gene: cyp4b1.2 / 550102
• XenbaseID: XB-GENE-963387
• Length: 515
• Species: Xenopus tropicalis
• Alignment Length: 493
• Identity: 143/493 - (29%)
• Similarity: 239/493 - (48%)
• Gaps: 78/493 - (15%)

  Fly    11 LTIWILVRKWTLLRLGSSLPGPWAFPLLGNAQMVGKL-------RPEYIFLVFTELRDRFGATYR 68
            |.:|  |.|:           |.||||     .:||.       .|:|..:||
 Frog    79 LMVW--VNKY-----------PNAFPL-----WIGKFFGTLIITDPDYAKVVF------------ 113

  Fly    69 LRLGPQLWVFLHSAEETRQALHDPTLRKADTFMQLEPLIGNGLLISHGAHWTRQRRLLTPAFQPQ 133
                               ...||.......|  |.|.||.||||..|..|.:.|||:||.|...
 Frog   114 -------------------GRSDPKTSTGYNF--LVPWIGKGLLILSGNTWFQHRRLITPGFHYD 157

  Fly   134 LLRSFAPAIGGHVERLVGRLG--ATRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQSVDHSPIIQ 196
            :|:.:...|....:.::..|.  :.:...:|:.:.:....||:|:..:.....:.|:...:..||
 Frog   158 VLKPYVSLISDSTKIMLDELDVYSNKDESVELFQHVSLMTLDSIMKCAFSYHSNCQTDKDNDYIQ 222

  Fly   197 AFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEKRAKELLDMGEPAGRA 261
            |.:..|.|..:|:......|:.|:..:.......:..:::|...:.||.:| |:||:..|...:.
 Frog   223 AVYDLSWLTQQRIRTFPYHSNLIYFLSPHGFRFRKACRIVHLHTDKVIGQR-KKLLESKEELEKV 286

  Fly   262 H-----NLLDTLLLAKFE-GQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLR 320
            .     :.||.||.:|.| ||.||..::|.|::||:|.|.|||::.:|::||.:|..||.|.:.|
 Frog   287 QKKRHLDFLDILLCSKDENGQGLSHEDLRAEVDTFMFEGHDTTSSGISWILYCMATHPEHQQKCR 351

  Fly   321 KELQDVALDE--TTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQS-TEIGGRTYCAGVTLW 382
            :|:.: ||.|  |.:.|.||.:||....|||.||||..||:..|:..:. |...||:..||:.:.
 Frog   352 EEISE-ALGERQTMEWDDLNRMPYTTMCIKESLRLYPPVPSVSRELAKPITFHDGRSLPAGMLVS 415

  Fly   383 INMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARL 447
            :.:|.:..:...:.||..|.|.|:.||:.: ...:.:::||:.||..|||:.:::..||:..|..
 Frog   416 LQIYAIHRNPNVWKDPEIFDPLRFSPENSS-KRHSHAFVPFAAGPRNCIGQNFAMNEMKVAVALT 479

  Fly   448 VREFQMELSPE--QAPLRLEAQMVLKAQQGINVSFLKQ 483
            ::.|  ||||:  :.||: :.|:||:::.||:| :||:
 Frog   480 LKRF--ELSPDLSKPPLK-QPQLVLRSKNGIHV-YLKK 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	125/426 (29%)
cyp4b1.2	NP_001017348.1	CYP4B-like	76..510	CDD:410771	141/488 (29%)