Protein Alignment Cyp311a1 and Cyp3a73

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_038945885.1
• Gene: Cyp3a73 / 498198
• RGDID: 1595705
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 541
• Identity: 126/541 - (23%)
• Similarity: 215/541 - (39%)
• Gaps: 130/541 - (24%)

  Fly     4 WPLLLITLTIWILVRKWTLLRLGS---------SLPGPWAFPLLG-------------------- 39
            |.||.|.|.::        .|.|:         .:|||...|.||
  Rat    12 WLLLAIILVLF--------YRFGTRTHGIFKKQGIPGPKPLPFLGTVLNYYRGLWKFDMECYKKC 68

  Fly    40 -----------------NAQMVGKLRPEYIFLVFTELRDRFGATYRLRLGPQLWVFLHSAEETRQ 87
                             :.:|:..:..:..|.|||..|:         :||
  Rat    69 GKIWGLFDGQTPVFAIMDTEMIKSVLVKECFSVFTNRRN---------IGP-------------- 110

  Fly    88 ALHDPTLRKADTFMQLEPLIGNGLLISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGR 152
                            ..::...:.::....|.|.|..|:|.|....|:...|.|..:.:.||..
  Rat   111 ----------------VGIMSKSISVAKDEEWKRYRAFLSPTFTSGRLKEMFPIIEHYGDILVKY 159

  Fly   153 L--GATRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQSVDHSPII------QAFHLSSKLLFKRM 209
            |  ...:|..|.:.|...|..:|.|..||....:::.:....|.:      |.|.....|....:
  Rat   160 LKQKVEKGKPLAMKEVFGAYSMDVITSTSFEVNINSINNPKDPFVEKVKKFQRFDFFDPLFLSVV 224

  Fly   210 INPLLSSDWIFQRTQLWRDLDEQL----------QVIHSQMESVIEKRAKELLDMGEPAGRAHNL 264
            :.|.|        |.::..|:..|          :.::...::.::.:.|..:|..:....|||.
  Rat   225 LFPFL--------TPIYEMLNICLFPKDSVAFFQKFVYRMKQTRLDSKHKHRVDFLQLMMNAHNN 281

  Fly   265 LDTLLLAKFEGQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALD 329
            ...    |...::||..||..:...|:||..:||::.:|||||:||..|::|.:|::|: |.||.
  Rat   282 SKD----KVSHKALSDIEIVAQAIIFIFASYETTSSTLSFVLYSLATHPDSQKKLQEEI-DRALP 341

  Fly   330 ETT--DLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDK 392
            ...  ..|.:..:.||:.::.|..|||.|.....|...:..::.|.....|..:.|..|.|.||.
  Rat   342 NKAPPTYDTVMEMEYLDMVLNETPRLYPIGYRLERVCKKDIKLDGVFIPKGSVVMIPFYTLQHDP 406

  Fly   393 EYYPDPYAFKPERWLPED-GAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELS 456
            :::|:|..|.|||:..|: |::.|  :.|:||..||..|||.|::|:.|||...::::.|..:|.
  Rat   407 QHWPEPEEFLPERFSKENKGSIDP--YVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQLC 469

  Fly   457 PE-QAPLRLEAQMVLKAQQGI 476
            .| |.||:|..|.:...::.|
  Rat   470 EETQIPLKLSRQRLFGPEKPI 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	107/435 (25%)
Cyp3a73	XP_038945885.1	CYP3A	67..493	CDD:410743	113/478 (24%)