DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp311a1 and Cyp313a3

DIOPT Version :9

Sequence 1:	NP_572780.3	Gene:	Cyp311a1 / 32170	FlyBaseID:	FBgn0030367	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_650170.2	Gene:	Cyp313a3 / 41488	FlyBaseID:	FBgn0038007	Length:	492	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	120/503 - (23%)
Similarity:	227/503 - (45%)	Gaps:	49/503 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLLITLTIWILVRKWTLLRL---GSSLPGPWAFPLLGNAQMVGKLRPEYIFL------VFTELRD 61
            ||.:.:..||.. .|:..||   ...:|||...|:||.|.       ||:..      :.|:..|
  Fly     7 LLAVGVCFWIYF-LWSRRRLYMMHFKIPGPMGLPILGIAF-------EYLITYKRKMSIRTKYMD 63

  Fly    62 RFGATYRLRLGPQLWVFLHSAEETRQALHDP-TLRKADTFMQ-LEPLIGNGLLISHGAHWTRQRR 124
            .:|:|..:.:||..:|.....:...:....| .|.::..|.: :....|:|||....:.|..:|:
  Fly    64 IYGSTCLVWVGPTPFVITRDPKIAEEIFLSPECLNRSSIFSKPVNSCTGDGLLSLEASKWVDRRK 128

  Fly   125 LLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRG-AFLEVTEPLFACLLDAIVDTSMGAQLDTQ- 187
            .|.|||:..:|.||.|......:.||..|.:..| ...:|.:.:..........|::|..:...
  Fly   129 NLNPAFKQNVLLSFLPIFNSEAKTLVAFLDSLVGQGEKKVRDDIVRWSFRIATQTTVGTDVKKDA 193

  Fly   188 SVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDL---DEQLQV----IHSQMESVIE 245
            |..:..:::::....|::...::.|       |...:::..|   :.|..:    ::..:.::::
  Fly   194 SFKNDSVLKSYETFMKIIVMNVLLP-------FTHNKIFSTLGGFETQKALAKSNVNKMIGTIVD 251

  Fly   246 KRAKELLDMGEPAGRAHNLLDTLLLAKFE---GQSLSRREIRDEINTFVFAGVDTTTAAMSFVLY 307
            |:.     |.:|...:...:.:::....|   ...:||.|::.|..:||.|..:||...:...|.
  Fly   252 KKL-----MTKPESGSQPEITSVINKAIELHRNGEMSREEVQSECCSFVVAAFETTGDTVYHALI 311

  Fly   308 ALAKFPETQTRLRKELQD---VALDETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTE 369
            .||.|||.|..:.:||::   ||.|.....|.|..:.:||.::.|.|||...||.|.|:|.:...
  Fly   312 LLAMFPEHQDTVYQELKELFPVAGDFEVTYDDLQRMVFLERVVNETLRLIPSVPFTPRETIRDFR 376

  Fly   370 I-GGRTYCAGVTLWINMYGLAHDKEYY-PDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIG 432
            : .|.....||.:.|:::....::::: .||.:|.|:.:||::.....| ::|||||.|...|||
  Fly   377 LSSGVVIPKGVGIGIDIFATHRNRDHWGTDPSSFNPDHFLPDNVRDRHP-YAYIPFSKGRRNCIG 440

  Fly   433 RRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINVSF 480
            .:|.|:..||..::::|..::..|.....|.....:.::..|...:.|
  Fly   441 WKYGLMSSKLALSKILRNCKVSTSFRYEDLEFVDNIGMELAQSPGLEF 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	112/474 (24%)
Cyp313a3	NP_650170.2	p450	33..463	CDD:299894	109/449 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442787
Domainoid	1	1.000	82	1.000	Domainoid score	I1949
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.790