DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp311a1 and Cyp313a2

DIOPT Version :9

Sequence 1:	NP_572780.3	Gene:	Cyp311a1 / 32170	FlyBaseID:	FBgn0030367	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_650169.3	Gene:	Cyp313a2 / 41487	FlyBaseID:	FBgn0038006	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	504	Identity:	124/504 - (24%)
Similarity:	218/504 - (43%)	Gaps:	51/504 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLLITLTIWI--LVRKWTLLRLGSSLPGPWAFPLLGNAQMV-----GKLRPEYIFLVFTELRDRF 63
            |:..:|.:||  |..:..|..|...|||....|||||:...     |::...      |...|:.
  Fly     7 LIAASLILWIRFLWSRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSSR------TTYMDKH 65

  Fly    64 GATYRLRLGPQLWVFLHSAEETRQALHDPTL--RKADTFMQLEPLIGNGLLISHGAHWTRQRRLL 126
            |:||...:|....|.....:...:.|..|..  |.:.|...|...:|.|||...|:.|..:|:.:
  Fly    66 GSTYMAWIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQGSKWMARRKHM 130

  Fly   127 TPAFQPQLLRSFAPAIGGHVERLVGRLGATRG-AFLEVTEPLFACLLDAIVDTSMGAQL-DTQSV 189
            .|||:..:|.||.|......:.||....:..| ...:|...|..........|::|..: ...:.
  Fly   131 NPAFKHSVLLSFLPIFNAETDLLVSVFDSFVGQGEKDVLSDLIRWSFAIATQTTLGTDVTKDDNF 195

  Fly   190 DHSPIIQAFHLSSKLLF---------KRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIE 245
            ::..|::.:....:|..         .::::.|...:|:.:|         ....|:..:.::::
  Fly   196 ENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFGLEWLRRR---------DASAINKMINNILD 251

  Fly   246 KRAKELLDMGEPAGRAHNLLDTLL---LAKFEGQSLSRREIRDEINTFVFAGVDTTTAAMSFVLY 307
            |:..     ..|.....:.|.|::   :..|....:|..|:..|.::.|.|..:|:...:.:.|.
  Fly   252 KKLN-----SNPENYCESELKTVIHRAIELFRNDEMSLMELGAECSSMVLAAFETSAHTVYYALV 311

  Fly   308 ALAKFPETQTRLRKELQD---VALD-ETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQST 368
            .||.|||.|..:..|:::   :|.. |.|..| |..|.||:.::.|.|||...||.:.|:|.:..
  Fly   312 LLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTD-LQQLVYLDRVLNETLRLMPSVPFSSRETLEDL 375

  Fly   369 EI-GGRTYCAGVTLWINMYGLAHDKEYYPDPYA-FKPERWLPEDGAVAPPAFSYIPFSGGPHVCI 431
            .: .|.....|:|:.|:::....:.:|:....| |.||.:|||......| :::||||.|...||
  Fly   376 RLSNGVVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHP-YAFIPFSKGKRNCI 439

  Fly   432 GRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINVSF 480
            |.||.|:..||...:::|.::::.|.....|.....||:|..|...::|
  Fly   440 GWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSPQLAF 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	115/476 (24%)
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	109/451 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442788
Domainoid	1	1.000	82	1.000	Domainoid score	I1949
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.790