DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp311a1 and Cyp4ac2

DIOPT Version :9

Sequence 1:	NP_572780.3	Gene:	Cyp311a1 / 32170	FlyBaseID:	FBgn0030367	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	NP_608917.3	Gene:	Cyp4ac2 / 33755	FlyBaseID:	FBgn0031694	Length:	511	Species:	Drosophila melanogaster

Alignment Length:	445	Identity:	130/445 - (29%)
Similarity:	228/445 - (51%)	Gaps:	27/445 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 VFTELRDRFGATYRLRLGPQLWVFLHS-------AEETRQALHDPTL-RKADTFMQLEPLIGNGL 111
            :|..:||   |:.:.:....||.|.|:       |||..:.|....| .|...:..|:|.:|.||
  Fly    71 IFNFMRD---ASAKAKGRNYLWYFFHAPMYNIVRAEEAEEILQSSKLITKNMIYELLKPFLGEGL 132

  Fly   112 LISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEPLFACLLDAIV 176
            |||....|..:|:.|||||..::|:||.........:||..|..:....||:.:.:....|:.:.
  Fly   133 LISTDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVLHQSVNMELELNQVIPQFTLNNVC 197

  Fly   177 DTSMGAQLD--TQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQ 239
            :|::|.:||  ::.:.:.   |:.|...:::.:|:.||...:...|.....:|.....|::.|..
  Fly   198 ETALGVKLDDLSEGIRYR---QSIHAIEEVMQQRLCNPFFYNIVYFFLFGDYRKQVNNLKIAHEF 259

  Fly   240 MESVIEKR----AKELLDMGEPAGR--AHNLLDTLLLAKFEGQSLSRREIRDEINTFVFAGVDTT 298
            ..::||||    ....|...:..|:  .:.:|||||.|:.:|| :..:.|.||:|||:|.|.|||
  Fly   260 SSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLDTLLAAEADGQ-IDHQGICDEVNTFMFEGYDTT 323

  Fly   299 TAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLDA--LNGLPYLEALIKEVLRLYTIVPTTG 361
            :..:.|.|..||...:.|.:..:|::.:. |::.|:..  .|.|.|:|.:|||.|||:..||..|
  Fly   324 STCLIFTLLMLALHEDVQKKCYEEIKYLP-DDSDDISVFQFNELVYMECVIKESLRLFPSVPFIG 387

  Fly   362 RQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGG 426
            |:..:...:.|........:.|::|.:..|..::.:|..|:|:|:.||:.....| |:::|||.|
  Fly   388 RRCVEEGVVNGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFFPENTVNRHP-FAFVPFSAG 451

  Fly   427 PHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINVSFL 481
            ...|||:::::|.:|:|.|.::|.|::........|..|..:||:.:|.|.|..:
  Fly   452 QRNCIGQKFAILEIKVLLAAVIRNFKILPVTLLDDLTFENGIVLRTKQNIKVKLV 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	130/442 (29%)
Cyp4ac2	NP_608917.3	p450	57..505	CDD:278495	130/442 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	7	7.060