DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp311a1 and Cyp4f39

DIOPT Version :9

Sequence 1:	NP_572780.3	Gene:	Cyp311a1 / 32170	FlyBaseID:	FBgn0030367	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	XP_006241152.1	Gene:	Cyp4f39 / 299566	RGDID:	1308796	Length:	550	Species:	Rattus norvegicus

Alignment Length:	500	Identity:	135/500 - (27%)
Similarity:	225/500 - (45%)	Gaps:	84/500 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RKWTLLRLGSSLPG-------------------PWAFPLLGNAQMVGKLRPEYIFLVFTELRDRF 63
            |.|.|..:...||.                   .|..|.|   .::..:.|:||       :...
  Rat    65 RHWLLGHMSMYLPNEKGLQNEKKVLDTMHHIILAWVGPFL---PLLVLVHPDYI-------KPVL 119

  Fly    64 GATYRLRLGPQLWVFLHSAEETRQALHDPTLRKADTFMQ--LEPLIGNGLLISHGAHWTRQRRLL 126
            ||:  ..:.|:                       |.|..  |:|.:|:|||||.|..|:|.||||
  Rat   120 GAS--AAIAPK-----------------------DEFFYSFLKPWLGDGLLISKGNKWSRHRRLL 159

  Fly   127 TPAFQPQLLRSFAPAIGGHVERLVGR----LGATRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQ 187
            ||||...:|:.:.......|..:..:    |........::.|.:....||::.........|.|
  Rat   160 TPAFHFDILKPYMKIFNQSVNIMHAKWRRHLAEGSVTSFDMFEHVSLMTLDSLQKCVFSYSSDCQ 224

  Fly   188 SVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEKRAKELL 252
            ......|.....||: |:.:|........|:|:..|...|...:....:|:....||::|.:.|.
  Rat   225 EKLSDYISSIIELSA-LVVRRQYRLHHYLDFIYYLTADGRRFRQACDTVHNFTTEVIQQRRRALR 288

  Fly   253 DMGEPA------GRAHNLLDTLLLAK-FEGQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALA 310
            ::|..|      |:..:.:|.||||| .||:.||..:||.|.:||:|.|.|||::.:|:.|:.||
  Rat   289 ELGAEAWLKAKQGKTLDFIDVLLLAKDEEGKELSDEDIRAEADTFMFEGHDTTSSGLSWALFNLA 353

  Fly   311 KFPETQTRLRKELQDVALD---ETTDLDALNGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEI-G 371
            |:||.|.:.|:|:|:|...   |..|.|.|..||:....|||.||.:..|....|:.|:..:: .
  Rat   354 KYPEYQDKCREEIQEVMKGRELEELDWDDLTQLPFTTMCIKESLRQFPPVTLISRRCTEDIKLPD 418

  Fly   372 GRTYCAGVTLWINMYGLAHDKEYYPD-----PYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCI 431
            ||....|:...:::||..::...:||     ||.|.|:  :|:..  :|.||  :|||.||..||
  Rat   419 GRIIPKGIICLVSIYGTHYNPLVWPDSKVYNPYRFDPD--IPQQR--SPLAF--VPFSAGPRNCI 477

  Fly   432 GRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGI 476
            |:.:::..|:::.|..:..|::.:. ....:|.:.:::|:.:.|:
  Rat   478 GQSFAMAEMRVVVALTLLRFRLSVD-RTRKVRRKPELILRTENGL 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	p450	30..480	CDD:278495	131/487 (27%)
Cyp4f39	XP_006241152.1	CYP4F	82..523	CDD:410772	130/482 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810