Protein Alignment Cyp311a1 and Cyp4f4

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_775146.1
• Gene: Cyp4f4 / 286904
• RGDID: 708363
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 502
• Identity: 153/502 - (30%)
• Similarity: 249/502 - (49%)
• Gaps: 37/502 - (7%)

  Fly     4 WPLLLITLTIWILVRKWT----LLRLGSSL-----PGPWAFPLLGNAQMVGKLRP-EYIFLVFTE 58
            |.|||:....|:|||..|    ..|....|     |..|.: .||:   :|.:.| |......|:
  Rat    19 WLLLLLIGASWLLVRVLTQTYIFYRTYQHLCDFPQPPKWNW-FLGH---LGMITPTEQGLKQVTK 79

  Fly    59 LRDRFGATYRLRLGPQLWVF-LHSAEETRQALH---DPTLRKADTFMQLEPLIGNGLLISHGAHW 119
            |...:...:...|||.|.:. |...:..|..|.   ...|::...:..|:|.:|:|||:|.|..|
  Rat    80 LVATYPQGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFLKPWLGDGLLLSDGDKW 144

  Fly   120 TRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGR---LGATRGAFLEVTEPLFACLLDAIVDTSMG 181
            :..||:|||||...:|:.:..........:..:   |.:...|.|::.:.:....||::......
  Rat   145 SCHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQDLASGGSARLDMFKNISLMTLDSLQKCVFS 209

  Fly   182 AQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEK 246
            ...:.|. ..|..|.|....|.|:.||....||.:|.::|.|...|...:..:::|:..::||:.
  Rat   210 FDSNCQE-KPSEYISAILELSALVAKRYQQLLLHTDSLYQLTHNGRRFHKACKLVHNFTDAVIQG 273

  Fly   247 RAKELL-----DMGEPAGRAHNL--LDTLLLAKFE-GQSLSRREIRDEINTFVFAGVDTTTAAMS 303
            |.:.|.     |:.:...|:..|  :|.|||.|.| |:.||..:||.|.:||:|.|.|||.:.:|
  Rat   274 RRRALPSQHEDDILKAKARSKTLDFIDVLLLTKDEDGKELSDEDIRAEADTFMFEGHDTTASGLS 338

  Fly   304 FVLYALAKFPETQTRLRKELQDVALD-ETTDL--DALNGLPYLEALIKEVLRLYTIVPTTGRQTT 365
            ::||.||:.||.|.|.|:|::::..| |:|::  |.|..||:|...|||.|||:..|....|:.|
  Rat   339 WILYNLARHPEYQERCRQEVRELLRDRESTEIEWDDLAQLPFLTMCIKESLRLHPPVTVISRRCT 403

  Fly   366 QSTEI-GGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHV 429
            |...: .||....||...||::...|:...:|||..:.|.|:.||:.....| .::||||.||..
  Rat   404 QDIVLPDGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRFDPENIKDRSP-LAFIPFSAGPRN 467

  Fly   430 CIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGI 476
            |||:.:::..||:..|..:..|:  :.|:....|.:.:::|:|:.|:
  Rat   468 CIGQTFAMNEMKVALALTLLRFR--VLPDDKEPRRKPELILRAEGGL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	133/432 (31%)
Cyp4f4	NP_775146.1	CYP4F	74..515	CDD:410772	135/443 (30%)