Protein Alignment Cyp311a1 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_058695.2
• Gene: Cyp4b1 / 24307
• RGDID: 2480
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 151/520 - (29%)
• Similarity: 253/520 - (48%)
• Gaps: 67/520 - (12%)

  Fly     1 MALWP----LLLITLTIW-ILVRKWTLLRLGSSLPGPWAFPLLGNA---QMVGKLRPEYIFLVFT 57
            :.||.    |::|.|.:: :|:|:..|.|...|.|||....|.|:|   |.:|.|..      ..
  Rat    13 LGLWASVVILMVIVLKLFSLLLRRQKLARAMDSFPGPPTHWLFGHALEIQKLGSLDK------VV 71

  Fly    58 ELRDRFGATYRLRLGPQLWVFLHSAEETRQALHDPTLRKA-------------DTFMQLEPLIGN 109
            ....:|...:.|..| |...||:        :::|...||             |.|:|   .||.
  Rat    72 SWAQQFPHAHPLWFG-QFVGFLN--------IYEPDYAKAVYSRGDPKAADVYDFFLQ---WIGK 124

  Fly   110 GLLISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGR--LGATRGAFLEVTEPLFACLL 172
            |||:..|..|.:.|:||||.|...:|:.:..........::.:  ..|:.....::...:....|
  Rat   125 GLLVLDGPKWFQHRKLLTPGFHYDVLKPYVAIFAESTRMMLDKWEKKASENKSFDIFCDVGHMAL 189

  Fly   173 DAIV-------DTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPL-LSSDWIFQRTQLWRDL 229
            |.::       |:.:|.:      |:|..:....|:  ||.::.|:.. ..:|:|:..|...|..
  Rat   190 DTLMKCTFGKGDSGLGHR------DNSYYLAVSDLT--LLMQQRIDSFQYHNDFIYWLTPHGRRF 246

  Fly   230 DEQLQVIHSQMESVIEKRAKELLDMGEP---AGRAH-NLLDTLLLAKFE-GQSLSRREIRDEINT 289
            ....::.|...:.||.:|...|.|..|.   ..|.| :.||.||..:.| |..||..|:|.|::|
  Rat   247 LRACKIAHDHTDEVIRQRKAALQDEKERKKIQQRRHLDFLDILLGVRDESGIKLSDAELRAEVDT 311

  Fly   290 FVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETT-DLDALNGLPYLEALIKEVLRL 353
            |:|.|.||||:.:|:.||.:|.:||.|...|:|::.:..|:.: ..|.|..:.||...:||..||
  Rat   312 FMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQDSFQWDDLAKMTYLTMCMKECFRL 376

  Fly   354 YTIVPTTGRQTTQS-TEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPA 417
            |..||...||..:. |.:.||:..||..:.:::|.|..:...:|||..|.|.|:.||:.|...|
  Rat   377 YPPVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVWPDPEVFDPLRFSPENAAGRHP- 440

  Fly   418 FSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINVSFLK 482
            |:::|||.||..|||:::::..||::||..:..|:..|.|.:.|::: .|::|:::.||:: :||
  Rat   441 FAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPIKV-PQLILRSKNGIHL-YLK 503

  Fly   483  482
              Rat   504  503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	129/443 (29%)
Cyp4b1	NP_058695.2	CYP4B-like	67..501	CDD:410771	131/462 (28%)