Protein Alignment Cyp311a1 and Cyp4a2

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001038235.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 501
• Identity: 150/501 - (29%)
• Similarity: 248/501 - (49%)
• Gaps: 51/501 - (10%)

  Fly     6 LLLITLTIWILVRKWTLLRLGS--SLPGPWAFPLLGNAQMVGKLRPEYIFLVFTELRDRFGATYR 68
            |:|.....:.|.|:|.|..|..  |.|..|   |.|:     .|:......|.|.:....||..:
  Rat    29 LVLFKAVQFYLRRQWLLKALEKFPSTPSHW---LWGH-----NLKDREFQQVLTWVEKFPGACLQ 85

  Fly    69 LRLGPQLWVFLHSAEETRQALHDP-----TLRKAD--TFMQLEPLIGNGLLISHGAHWTRQRRLL 126
                   |:   |....|..|:||     .|.::|  .:..|.|.||.|||:.:|..|.:.||:|
  Rat    86 -------WL---SGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRML 140

  Fly   127 TPAFQPQLLRSFAPAIGGHVERLVGRLGA--TRGAFLEVTEPLFACLLDAIVDTSM----GAQLD 185
            ||||...:|:.:...:...|..::.:...  .:...||:...:....||.::..:.    ..|||
  Rat   141 TPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLD 205

  Fly   186 TQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEKRAKE 250
            ..|..::..::..   :.|:|.|:.:....:..|:..:...|......|:.|...:.||:.|..:
  Rat   206 VNSRSYTKAVEDL---NNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQ 267

  Fly   251 LL---DMGEPAGRAH-NLLDTLLLAKFE-GQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALA 310
            |.   ::.:...:.| :.||.||.||.| |:|||..::|.|::||:|.|.|||.:.:|:|.||||
  Rat   268 LQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALA 332

  Fly   311 KFPETQTRLRKELQDVALDETT-DLDALNGLPYLEALIKEVLRLYTIVPTTGRQ-TTQSTEIGGR 373
            ..||.|.|.|:|:|.:..|.|: ..|.|:.:||....|||.||||:.||:..|: ::..|...||
  Rat   333 THPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGR 397

  Fly   374 TYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFS--YIPFSGGPHVCIGRRYS 436
            :...|:.:.|.:|||.|:..|:|:|..|.|.|:.|:.     |..|  |:|||||...|||::::
  Rat   398 SIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDS-----PRHSHAYLPFSGGARNCIGKQFA 457

  Fly   437 LLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINVSFLK 482
            :..:|:..|..:..|::...|.:.|:.: .::|||::.||::...|
  Rat   458 MNELKVAVALTLLRFELLPDPTRIPVPM-PRLVLKSKNGIHLRLKK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	134/435 (31%)
Cyp4a2	NP_001038235.1	CYP4B-like	69..499	CDD:410771	136/448 (30%)