Protein Alignment Cyp311a1 and Cyp26b1

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_780684.1
• Gene: Cyp26b1 / 232174
• MGIID: 2176159
• Length: 512
• Species: Mus musculus
• Alignment Length: 522
• Identity: 127/522 - (24%)
• Similarity: 208/522 - (39%)
• Gaps: 103/522 - (19%)

  Fly     6 LLLITLTIWILVRKWTLLRLGS-SLP---GPWAFPLLGNA-----QMVGKLRPEYIFLVFTELRD 61
            ||.::..:|.|  :|...|..| .||   |...|||:|..     |..|         ..:..|:
Mouse    25 LLAVSQQLWQL--RWAATRDKSCKLPIPKGSMGFPLIGETGHWLLQGSG---------FQSSRRE 78

  Fly    62 RFGATYRLRLGPQLWVFLHSAEETRQ-ALHDPTLRKADTFMQLEPLIG-NGLLISHGAHWTRQRR 124
            ::|..::..|..:..:.:..||..|: .|.:..|...:.......|:| |.:..|.|.....:|:
Mouse    79 KYGNVFKTHLLGRPLIRVTGAENVRKILLGEHQLVSTEWPRSARVLLGPNTVANSIGDIHRNKRK 143

  Fly   125 LLTPAFQPQLLRSFAPAIGGHVERLVGRLGATRGAFLEVTEPLFACLLDAIVDTSMGAQLDTQSV 189
            :.:..|..:.|.|:.|.|     :||                        |.||........::
Mouse   144 VFSKIFSHEALESYLPKI-----QLV------------------------IQDTLRAWSSQPEA- 178

  Fly   190 DHSPIIQAFHLSSKLLFKRMINPLLSSDWIFQRTQLWRDLDEQLQVIHSQMESVIEK-------- 246
                 |..:..:.:|.|:..:..||.    |...:  .||....:|....:|:|...
Mouse   179 -----INVYQEAQRLTFRMAVRVLLG----FSIPE--EDLGHLFEVYQQFVENVFSLPVDLPFSG 232

  Fly   247 -----RAKELLDMG-EPAGRA----------HNLLDTLL-LAKFEGQSLSRREIRDEINTFVFAG 294
                 :|:::|..| |.|.|.          .:.||.|: .:|..|:.::.:|::|.....:||.
Mouse   233 YRRGIQARQILQKGLEKAIREKLQCTQGKDYSDALDILIESSKEHGKEMTMQELKDGTLELIFAA 297

  Fly   295 VDTTTAAMSFVLYALAKFPETQTRLRKELQDVAL--------DETTDLDALNGLPYLEALIKEVL 351
            ..||.:|.:.::..|.|.|....:||:||:...|        :.|..||.|:.|.||:.:||||:
Mouse   298 YATTASASTSLIMQLLKHPAVLEKLREELRAQGLLHGGGCPCEGTLRLDTLSSLRYLDCVIKEVM 362

  Fly   352 RLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGL--AHD-KEYYPDPYAFKPERWLPEDGAV 413
            ||:|.|....|...|:.|:.|.....|   |..||.:  .|| ...:.|...|.|:|:.......
Mouse   363 RLFTPVSGGYRTVLQTFELDGFQIPKG---WSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSED 424

  Fly   414 APPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPLRLEAQMVLKAQQGINV 478
            ....|.|:||.||...|:|:..:.|.:|:|...|....:.||:....| |:....||....|::|
Mouse   425 KDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFP-RITLVPVLHPVDGLSV 488

  Fly   479 SF 480
            .|
Mouse   489 KF 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	108/451 (24%)
Cyp26b1	NP_780684.1	CYP26B1	60..490	CDD:410730	113/483 (23%)