Protein Alignment Cyp311a1 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_035669.3
• Gene: Tbxas1 / 21391
• MGIID: 98497
• Length: 533
• Species: Mus musculus
• Alignment Length: 551
• Identity: 153/551 - (27%)
• Similarity: 240/551 - (43%)
• Gaps: 105/551 - (19%)

  Fly     6 LLLITLTIWIL-VRKW-------TLLRLGSSLPGPWAFPLLGNAQMVGKLRPEYIFLVF------ 56
            ::.:||.:.:| :.||       .|.:||...|.|  .|.:||             |:|
Mouse    15 IVTVTLLVALLALLKWYSMSAFSRLEKLGIRHPKP--SPFVGN-------------LMFFRQGFW 64

  Fly    57 ---TELRDRFGATYRLRLGPQLWVFLHSAEETRQALHDPTLRKADTFMQ-----LEP-LIGNGLL 112
               .|||:|:|......||.::.|.:...:..:|.|    :.....|..     ||| ::.:.:|
Mouse    65 ESQLELRERYGPLCGYYLGRRMHVVISEPDMIKQVL----VENFSNFSNRMASGLEPKMVADSVL 125

  Fly   113 ISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVG---RLGATRGAFLEVTEPLFAC-LLD 173
            :.....|...|..|..:|.|:.|....|.|....|.||.   |..|:|.||  ..:..:.| .:|
Mouse   126 LLRDRRWEEVRGALMSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAF--NIQRCYCCYTID 188

  Fly   174 AIVDTSMGAQLDTQSVDHSPIIQAFHLSSKLLFKRMINPLLSSDWIF-------QRTQLWRDLDE 231
            .:...:.|.|:|:|:....|.:|....:|.....|   |||.....|       .|....::.||
Mouse   189 VVASVAFGTQVDSQNSPEDPFVQHCRRASTFCIPR---PLLVLILSFPSIMVPLARILPNKNRDE 250

  Fly   232 QLQVIHSQMESVI--------EKRAKELLDMGEPAGRAHNLLDTLLLAKFEG-----QSLSRREI 283
            .....::.:.:||        |:|.::.|.|...|..:.|.:..      ||     :|||..|.
Mouse   251 LNGFFNTLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGV------EGFDMVPESLSSSEC 309

  Fly   284 R------------------DEI--NTFVF--AGVDTTTAAMSFVLYALAKFPETQTRLRKELQDV 326
            .                  |||  ..|:|  ||.:..|..:||:.|.||..|:.|.||.||: |:
Mouse   310 TKEPPQRCHPTSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEV-DL 373

  Fly   327 ALDE--TTDLDAL-NGLPYLEALIKEVLRLYTIVPTTGRQTTQSTEIGGRTYCAGVTLWINMYGL 388
            .:.:  ..:..:| .|||||:.:|.|.||:|.......|:..|..|:.|:...||..|.|.:..|
Mouse   374 FMGKHPAPEYHSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQRIPAGTVLEIAVGAL 438

  Fly   389 AHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQM 453
            .||.|::|:|..|.|||:..|......| |:|:||..||..|:|.|..||::||...:::.:|:.
Mouse   439 HHDPEHWPNPETFDPERFTAEARLQRRP-FTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRF 502

  Fly   454 ELSPE-QAPLRLEAQMVLKAQQGINVSFLKQ 483
            |.||| |.||:||::..|..:.|:.:..:.:
Mouse   503 EASPETQVPLQLESKSALGPKNGVYIKIVSR 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	134/469 (29%)
Tbxas1	NP_035669.3	cytochrome_P450	74..527	CDD:477761	134/469 (29%)