Protein Alignment Cyp311a1 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 130/522 - (24%)
• Similarity: 223/522 - (42%)
• Gaps: 108/522 - (20%)

  Fly     8 LITLTIWILVRKWTL-LRLGSSLPGPWAFPLLGNAQMVGKLRPEYIFLV-FTELRDRFGATYRLR 70
            ::|..:||    ||. :|.|  :.||...|.:|...::  |..|...|: ..|...::|..|...
 Worm    17 ILTYYLWI----WTYWMRKG--VKGPRGRPFVGVLDVL--LEHETPGLIKLGEWTKKYGKVYGYT 73

  Fly    71 LGPQLWVFLHSAEETRQALHDPTLRKADTF--MQLEPLIGN-------GLLISHGAHWTRQRRLL 126
            .|.|..:.:...    ..:|:..:::.|.|  .:|.|:.||       .||.:.|..|.|.|.:.
 Worm    74 DGTQRTLVVADP----AMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLLAAQGYRWKRLRTIS 134

  Fly   127 TPAFQPQLLRSFAPAIGG-------HVERLVGRLGATRGA--------FLEVTEPLFACLLDAIV 176
            :.:|....|:.....:..       |:|:      .|.|.        :.|.|       :|.|.
 Worm   135 SQSFSNASLKKMKRTVEDSALELLRHIEK------QTAGGEQIDMLRFYQEYT-------MDVIG 186

  Fly   177 DTSMGAQLDTQSVDHSPII----QAFHLSSK--LLFKRMINPLLSSDWIFQRTQLWRDLDEQLQV 235
            ..:|| |.|:. :..:||:    :.|..|.|  :|..::..|:         .|..|||..:...
 Worm   187 RFAMG-QTDSM-MFKNPIVNVVREIFCGSRKNLMLICQVFPPI---------GQFIRDLTFKFPR 240

  Fly   236 I-----HSQMESVIEKR-AKELLDMGEPAGRAHNLLDTLLLAKFEG--------QSLSRREIR-- 284
            |     :|.|:.|:..| |:...:.|..:|...:.:|..|.|:.:.        :..|:|.::
 Worm   241 IPAFKLYSIMQDVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEAREDFSKRNLKIT 305

  Fly   285 -----DEI----NTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLDALNGL 340
                 ||:    ..|:..|.|||..::|:|.|.||..|:.|.::.:|:.........:.:.|..|
 Worm   306 KELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFGTSEVEFEKLGRL 370

  Fly   341 PYLEALIKEVLRLYTIVP-TTGRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYY-PDPYAFKP 403
            .|::.:|||.||||.:.. :..|:..::|.:.|....|||.:.::.:.|.:|.|.: .|...|||
 Worm   371 KYMDCVIKEALRLYPLASISNSRKCMKTTTVNGVKIEAGVYVQMDTWSLHYDPELWGEDVKEFKP 435

  Fly   404 ERW-----LPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMEL-SPEQAPL 462
            |||     |...||       |:||..||..|||.|.:::..|:|...|::.:..|. :..:.||
 Worm   436 ERWSTDEPLEHKGA-------YLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFETGNKTRIPL 493

  Fly   463 RL 464
            :|
 Worm   494 KL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	115/464 (25%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	115/466 (25%)