Protein Alignment Cyp311a1 and cyp-13A3

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_496110.1
• Gene: cyp-13A3 / 188359
• WormBaseID: WBGene00011675
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 521
• Identity: 133/521 - (25%)
• Similarity: 224/521 - (42%)
• Gaps: 79/521 - (15%)

  Fly     1 MALWPLLLITLTI-------WILVRKWTL-LRLGSSLPGPWAFPLLGNAQMVGKLRPEYIFLVFT 57
            |:|..|:.|.|.|       ||    |:. :|.|  :.||...|..|...........:|.
 Worm     1 MSLSILIAIALFIGVFTYYLWI----WSFWMRKG--IKGPRGLPFFGIINAFQSYEKPWIL---- 55

  Fly    58 ELRDRFGATYRLRLGPQLWVFLHSAEET-----RQALHDPTLRKADTF--MQLEPLIGN------ 109
                |.| .:....|| ::.|....|:|     .:.:|:..:::.|.|  .:..||.|:
 Worm    56 ----RLG-DWTKEYGP-MYGFTDGVEKTLVVSDPEFVHEVFVKQFDNFYARKQNPLQGDPDKDPR 114

  Fly   110 -GLLISHGAHWTRQRRLLTPAFQPQLLRSFAPAIGGHVERLVGRL--GATRGAFLEVTEPLFACL 171
             .|:.|.|..|.|.|.|.:|.|..:.||.....:...|..::..|  |...|..:::.|......
 Worm   115 IHLVTSQGHRWKRLRTLASPTFSNKSLRKIFSTVEESVAEMMRHLEKGTAGGKTIDILEYYQEFT 179

  Fly   172 LDAIVDTSMGAQLDTQSVDH---SPIIQAFHLSSKLLFKRM-INPLLSS--DWIFQRTQLWRDLD 230
            :|.|...:|| |..:...::   ..|...|:....::|... |.|...|  .|.|.:....:.:.
 Worm   180 MDIIGKIAMG-QSGSMMFENPWLDKIRAIFNTRGNIIFIICGIVPFTGSIFRWFFSKVPTAQTVT 243

  Fly   231 EQLQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLDTLL---------------------LAKFE 274
            ..:..:...:...:|:||.:.....|.:|...:.:|..|                     :.|.:
 Worm   244 SLMHTLEIALTKRVEQRAADEKAGIESSGEPQDFIDLFLDVQADTDFLEDETKNGFARSQIVKVD 308

  Fly   275 GQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLDALNG 339
             :.|:..||..::..|:.||.|||..::|:..|.||:.||.|.:|::|:.....|.....|.|:.
 Worm   309 -KHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDRECPDPEVTFDQLSK 372

  Fly   340 LPYLEALIKEVLRLYTIVPTT-GRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYY-PDPYAFK 402
            |.|:|.:|||.||||.:.... .|:..:||.:.|.....|..:..:.:.|.:|.::: .:...||
 Worm   373 LKYMECVIKETLRLYPLASIVHNRKCMKSTTVLGMKIEEGTNVQADTWTLHYDPKFWGENANEFK 437

  Fly   403 PERWLPEDG---AVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPE-QAPLR 463
            ||||  |.|   |||..|  |:||..||.:|||.|.:.:..|:|.|::::::.:|.:.| ..||:
 Worm   438 PERW--ESGDEQAVAKGA--YLPFGLGPRICIGMRLAYMEEKMLLAQILKKYSLETTFETHIPLK 498

  Fly   464 L 464
            |
 Worm   499 L 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	116/450 (26%)
cyp-13A3	NP_496110.1	CYP3A-like	63..509	CDD:410678	115/444 (26%)