Protein Alignment Cyp311a1 and cyp-13A4

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_496111.1
• Gene: cyp-13A4 / 188355
• WormBaseID: WBGene00011671
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 523
• Identity: 127/523 - (24%)
• Similarity: 221/523 - (42%)
• Gaps: 106/523 - (20%)

  Fly     9 ITLTIWILVRKWTL-LRLGSSLPGPWAFPLLG------NAQMVGKLRPEYIFLVFTELRDRFGAT 66
            :|..|||    |:. :|.|  :.||..||..|      :.:..|.|:       ..|...::|:.
 Worm    16 LTYYIWI----WSFWIRKG--VKGPRGFPFFGVILKFHDYENPGLLK-------LGEWTKKYGSI 67

  Fly    67 YRLRLGPQLWVFLHSAEETRQALHDPTLRKADTF--MQLEPLIGN-------GLLISHGAHWTRQ 122
            |.:..|.:..:.:.:.|    .:|:..:::.|.|  .:..|:.|:       .|:::.|..|.|.
 Worm    68 YGITEGVEKTLVVSNPE----FVHEVFVKQFDNFYGRKTNPIQGDPNKNKRAHLVLAQGHRWKRL 128

  Fly   123 RRLLTPAFQPQLLRSFAPAIGGHVERLVGRL--GATRGAFLEVTEPLFACLLDAIVDTSMGAQLD 185
            |.|.:|.|..:.||.....:...|..|:..|  .:.:|..:::.:......||.|...:||   .
 Worm   129 RTLASPTFSNKSLRKIMSTVEETVVELMRHLDEASAKGKAVDLLDYYQEFTLDIIGRIAMG---Q 190

  Fly   186 TQSVDHSPIIQAFHLSSKLLFKRMINPLLSS-DWIFQR---------------TQLWRDLDEQ-- 232
            |:|               |:|:   ||:|.. ..||::               ..|.|.|..:
 Worm   191 TES---------------LMFR---NPMLPKVKEIFKKGGKMPFLIAGVFPIAGTLMRQLFMKFP 237

  Fly   233 --------LQVIHSQMESVIEKRAKELLDMGEPAGRAHNLLD----------------TLLLAKF 273
                    :..:...:...:|:||.:.....||:|...:.:|                ||..||.
 Worm   238 KFSPAFGIMNTMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDARANVDFIEEESTLGFAKS 302

  Fly   274 E----GQSLSRREIRDEINTFVFAGVDTTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDL 334
            |    .:.|:..||..::..|:.||.|||..::|:..|.||..||.|.:|::|:.....|.....
 Worm   303 EVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDRECPDPEVTF 367

  Fly   335 DALNGLPYLEALIKEVLRLYTIVPTT-GRQTTQSTEIGGRTYCAGVTLWINMYGLAHD-KEYYPD 397
            |.::.|.|:|.::||.||:|.:.... .|:..:.|.:.|.....|..:.::.:.|.:| |.:..|
 Worm   368 DQISKLKYMECVVKEALRMYPLASLVHNRKCMKKTNVLGVEIDEGTNVQVDTWTLHYDPKVWGDD 432

  Fly   398 PYAFKPERWLPEDGAVAPPAFSYIPFSGGPHVCIGRRYSLLLMKLLTARLVREFQMELSPE-QAP 461
            ...||||||...|....... .|:||..||.:|||.|.:::..|||...:::::..:.|.| :.|
 Worm   433 ASEFKPERWETGDELFYAKG-GYLPFGMGPRICIGMRLAMMEEKLLLTHILKKYTFDTSTETEIP 496

  Fly   462 LRL 464
            |:|
 Worm   497 LKL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	112/461 (24%)
cyp-13A4	NP_496111.1	CYP3A-like	63..511	CDD:410678	112/463 (24%)