Protein Alignment Cyp311a1 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_572780.3
• Gene: Cyp311a1 / 32170
• FlyBaseID: FBgn0030367
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 113/492 - (22%)
• Similarity: 221/492 - (44%)
• Gaps: 62/492 - (12%)

  Fly     8 LITLTIWILV--RKWTLLRLGSSLPGPWAFPLLGN----AQMVGKLRPEYIFLVFTELRDRFGAT 66
            :.|..|:|::  |:...||....|.||.....|||    |:...||..:.....|.||.:::|.|
 Worm    13 IFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDANRWFNELHEQYGET 77

  Fly    67 YRLRLGPQLWVFLHSAEETRQA----LHDPTLRKADTFMQLEPLIGNGLLISHGAHWTRQRRLLT 127
            :.:..|.|:.:.:.:.::.::.    ..:.:.|...:..:...|..:.|:.|:.:.|...|..:.
 Worm    78 FGIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMNSYSSGWKHTRSAIA 142

  Fly   128 PAFQPQLLRSFAPAIGGHVERLVG--RLGATRGAFLEVTEPLFACLLDAI------VDTS----- 179
            |.|....:::....|...|:..:.  |..|:.|...::.:......||.|      :|::
 Worm   143 PIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLDVIGKCAFAIDSNCQRDR 207

  Fly   180 -----MGAQLDTQSVD--HSPIIQAFHLSSKLLFKRMINPLLSSDW--IFQRTQLWRDLDEQLQV 235
                 :.|:....::|  ||.||.|    |.||      |.||:.|  :::.|.|   .|.::.:
 Worm   208 NDVFYVNAKKYISNIDIRHSKIIAA----SVLL------PELSTFWKALYKYTPL---ADAEIPL 259

  Fly   236 IHSQMESVIEKRAKELLDMGEPAGRAHNLLD--TLLLAKFEGQS--LSRREIRDEINTFVFAGVD 296
            :.. :.:|.|:|.         .|...:.:|  .|||.:.:.:|  ::::|:.:....|:.||.:
 Worm   260 VEG-LSNVYERRR---------GGEGSDSVDLLKLLLNREDDKSKPMTKQEVIENCFAFLLAGYE 314

  Fly   297 TTTAAMSFVLYALAKFPETQTRLRKELQDVALDETTDLDALNGLPYLEALIKEVLRLY-TIVPTT 360
            ||:.||::..|.|:|:|..|.:|.:|:.:...:.....|:::.:.||:.:.||.||.| .::...
 Worm   315 TTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKENGGLTYDSIHNMKYLDCVYKETLRFYPPVIHFI 379

  Fly   361 GRQTTQSTEIGGRTYCAGVTLWINMYGLAHDKEYYPDPYAFKPERWLPEDGAVAPPAFSYIPFSG 425
            .|...:...|.|:.|..|..:....:.:..:.|.:..|..|.|||:  |:......:..:|||..
 Worm   380 RRLCREDITIRGQFYPKGAIVVCLPHTVHRNPENWDSPEEFHPERF--ENWEEKSSSLKWIPFGV 442

  Fly   426 GPHVCIGRRYSLLLMKLLTARLVREFQMELSPEQAPL 462
            ||..|:|.|::.:..|....:|:..|:::....:|.|
 Worm   443 GPRYCVGMRFAEMEFKTTIVKLLDTFELKQFEGEADL 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp311a1	NP_572780.3	cytochrome_P450	64..478	CDD:477761	95/430 (22%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	95/432 (22%)